하이브리드 스캐폴드의 간헐적인 기계적 자극에 대한 영향 The Effect of Intermittent Mechanical Stimulation on Hydrogel Scaffold
한국기계기술학회지
(韓國機械技術學會誌)
제15권 제6호
(2013.12)
pp.1007-1012
pp.1007-1012
한국기계기술학회
(Korean Society of Mechanical Technology)
초록
Mechanical stimulation has been reported to improve cell growth in bone and cartilage regeneration. Various research groups have described their own bioreactors that stimulate cell-seeded scaffolds. We have developed a bioreactor capable of applying controlled compressive loading to a cell-encapsulated agarose hydrogel. To compare the effect of mechanical stimulation on agarose hydrogel, we used one control group (static mode) and five experimental groups. The results show that the intermittent_3sec conditions improve proliferation of cells better than the other conditions studied.
키워드
목차
Abstract
1. Introduction
2. Fabrication of Bioreactor
3. Materials and Methods
3.1 Cell culture
3.2 Fabrication of hydrogel scaffold
3.3 Modes of compression stimulation
3.4 Analysis of flow proliferation and fluorescence images
4. Results and Discussions
5. Conclusion
Acknowledgment
References
1. Introduction
2. Fabrication of Bioreactor
3. Materials and Methods
3.1 Cell culture
3.2 Fabrication of hydrogel scaffold
3.3 Modes of compression stimulation
3.4 Analysis of flow proliferation and fluorescence images
4. Results and Discussions
5. Conclusion
Acknowledgment
References
저자