This paper is concerned with the mechanical design of hyperbaric oxygen chamber for multi-users using stress analysis. HBOT(Hyperbaric Oxygen Therapy) is very effective medical equipment for increasing the concentration of melted oxygen in human and animal body. The hyperbaric oxygen supplies to the impaired cell of human and animal to recover the healthy condition. This research reported the design specifications and mechanical safety of hyperbaric oxygen chamber using computational stress analysis with CATIA program. The result from this research can be used for making the practical HBOT equipment for multi-users and to manufacture the real model