SGT 세포주에 미치는 Taxol의 Apoptosis 효과 Apoptotic Effect of Taxol on SGT Cell Line
대한구강악안면병리학회지
제32권 제3호
(2008.09)
pp.139-142
pp.139-142
대한구강악안면병리학회
(Korean Academy Of Oral And Maxillofacial Pathology)
초록
Taxol(paclitaxel) is used in chemotherapy against several cancer. Treatment of tumor cell lines with taxol induces apoptosis, but exact mechanism is not sufficiently understood. The purpose of this study was to investigate apoptosis by the inhibitory effect of paclitaxel on the motility properties of human salivary gland adenocarcinoma cell lines. Paclitaxel inhibited cell motility induced by soluble and immobilized attractant. It suggested that paclitaxel would be a potent inhibitor of salivary gland adenocarcinoma cell motility independent of its cytotoxic and apoptotic activity.
목차
I. Introduction
II. Materials and Methods
1. Drug Preparation and Cell Culture
2. MTT Assay
3. Motility Assays
III. Results
IV. Discussions
V. References
II. Materials and Methods
1. Drug Preparation and Cell Culture
2. MTT Assay
3. Motility Assays
III. Results
IV. Discussions
V. References
저자