KOREASCHOLAR

Adenosquamous carcinoma (ASC) is a rare malignant epithelial tumor in the oral cavity. It is regarded as a variant of squamous cell carcinoma (SCC) because ASC originates from the surface epithelium, has similar clinical features, and includes SCC portion which is histologically identical to the traditional form. This case report deals with two cases of ASC occurring in the oral mucosa of old male patients. Both case has tubular structures lined by cuboidal, basaloid, or small round cells under the conventional SCC component, which was reminiscent of the glandular differentiation of adenocarcinoma. On immunohistochemical studies, the glandular component of ASC showed positivity to CK-pan, CK7 and HMWCK, while the dysplastic squamous cells exhibited negativity to CK7. Accordingly, CK7 as well as morphological findings can lead towards differentiating ASC from other variants with gland-like structures, such as basaloid squamous cell carcinoma and adenoid squamous cell carcinoma.

I. 서론
 II. 증례보고
  1. Case 1
  2. Case 2
 III. 고찰
 IV. 참고문헌

• 조영아(서울대학교 치의학대학원 구강병리학교실) | Young Ah Cho
• 윤혜정(서울대학교 치의학대학원 구강병리학교실) | Hye Jung Yoon
• 홍성두(서울대학교 치의학대학원 구강병리학교실) | Seong Doo Hong
• 이재일(서울대학교 치의학대학원 구강병리학교실) | Jae Il Lee
• 홍삼표(서울대학교 치의학대학원 구강병리학교실) | Sam Pyo Hong correspondence