선치성낭: 7 증례 보고 및 Cytokeratin 발현에 관한 연구 Glandular Odontogenic Cysts : Report of Seven Cases and Analysis of Cytokeratin Expression
pp.359-366
Glandular odontogenic cyst (GOC) is a rare odontogenic cyst, which shows cystic structures lined by stratified squamous epithelium with various thickness. Glandular duct-like spaces lined by eosinophilic cuboidal or columnar cells constitute the epithelial surface. The purpose of this study was to present 7 cases of GOC retrieved from the files of the Department of Oral Pathology, Seoul National University Dental Hospital and to investigate the immunohistochemical expression of cytokeratins (CKs) in the epithelial components. A total of 7 GOCs were reviewed clinically and radiographically and immunostainning for CK 5, 7, 14, 18 and CK-pan were performed. There were five males and two females aged from 36 to 53 years (mean 45 years). Maxilla was more affected than mandibles (6:1). Radiographically, all cases showed multilocular radiolucencies with well-defined borders. Histologically, lining epithelium of GOC was composed of nonkeratinized stratified epithelial cells with focal plaque-like or whirl pool-like thickenings. Surface epithelial layer contained eosinophilic cuboidal cells or mucous cells. Mucin pools of microcystic areas was also detected in the epithelium. Immunohistochemical study demonstrated that epithelium of GOCs was positively reactive for CK 5 7, 14 and CK-pan with a slight variation in their patterns and there was no reaction for CK 18.
II. 연구 대상 및 방법
1. 연구 대상
2. 면역조직화학적 검사
III . 결과
1. 임상 소견
2. 조직병리학적 소견
3. 면역조직화학적 소견
IV. 고찰
V. 결론
VI. 참고문헌