Myoepithelioma is a rare tumor that seldom occur in the parapharyngeal space region. And an accurate diagnosis of myoepithelioma is very difficult due to its unusual location and cellular variation. Therefore, misdiagnosis of this neoplasm as more aggressive tumor can lead to unnecessary treatment. We experienced extremely rare case of myoepithelioma arising in the deep lobe of parotid gland that is extended in the parapharyngeal space and reported it to a literature review.