KOREASCHOLAR

A blood test is a laboratory analysis performed on a blood sample that is usually extracted from a vein in the arm using a needle, or via fingerprick. They are used to determine physiological and biochemical states, such as disease, mineral contents, drug effectiveness, and organ function. Although the term blood test is used, most routine tests (except for most haematology) are done on plasma or serum, instead of blood cells. Main advantage of using saliva in diagnostics is easy and non invasive sample taking compared to peripheral blood. According to the study published, saliva contains more than 20 percent of the proteins found in blood. The purpose of present study is to compare biochemical enzymes in saliva and in blood serum and to evaluate the usefulness of saliva specimens instead of blood in dental clinic. The saliva from 215 healthy over 50 years of aged people lived in Dong-gu district, Gwangu city was collected and the analysis was performed by six enzyme-linked immunosorbent assays (ELISA). ELISA results were compared with blood chemistry results. The values or patterns on Alanine Aminotransperase (ALT), Aspartate Aminotransperase (AST), Cholesterol and Triglyceride in saliva were not correlated with those in blood serum. However, Albumine and γ-glutamyl transpeptidase (γ-GTP) were followed the positive relationship with blood chemistry. These result showed that detection and identification of Albumine and γ-GTP level could be established by saliva ELISA analysis, so that ELISA assay on saliva could be useful alternative to serum testing.

I. INTRODUCTION
 II. MATERIALS AND METHODS
  1. Population and Saliva
  2. Blood chemistry
  3. Enzyme-linked immunosorbent assays (ELISA)
  4. Statistical analysis
 III. RESULTS
  1. Properties of participants
  2. Correlation of salivary ALT with serum ALT
  3. Correlation of salivary AST with serum AST
  4. Correlation of salivary cholesterol withserum cholesterol
  5. Correlation of salivary triglyceride withserum triglyceride
  6. Correlation of salivary albumin with serumalbumin
  7. Correlation of salivary γ-GTP with serumγ-GTP
 IV. DISCUSSION
 V. CONCLUSIONS
 VI. REFERENCES

• 조성훈(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Sung Hoon Cho
• 김서연(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Seo Yune Kim
• 고영종(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Young Jong Ko
• 임원봉(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Won Bong Lim
• 오미라(Department of Statistics, Chonnam National University) | Mi Ra Oh
• 김지선(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Ji Sun Kim
• 김인애(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | In Ae Kim
• 권혁일(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Hyuk Il Kwon
• Sandeep Karna(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University)
• 김옥준(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Ok Joon Kim
• 최홍란(Dental Research Institute, Department of Oral Pathology, School of Dentistry, Chonnam National University) | Hong Ran Choi correspondence