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구강에 발생한 다발성 원발성 편평세포암종 -3례보고- Multiple primary squamous cell carcinoma in oral cavity -A report of three cases-

차충민, 김현실, 김태규, 차인호, 육종인, 김진
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대한구강악안면병리학회지
제28권 제3호 (2004.09)
pp.195-202
대한구강악안면병리학회 (Korean Academy Of Oral And Maxillofacial Pathology)
초록

Squamous cell carcinoma comprises about 95% of oral cancers. 까le gene디C 없mage in carcinogen-exposed fields is accumulated to transforrn norrnal mucosa in dysplas디c tissue and fmally invasive carcinoma through multistep process. This carcinogenic process has been a cause of the development of secondary tumors after the removal of primary carcmoma. πle improvement of therapeutic modalities of oral cancer has driven into the increase of multiple cancer occurrence in head and neck region. We experienced 3 pa디ents who had mul디ple squamous cell carcinomas in oral cavlty. π1ÎS study aimed to report multiple pr따laπ squamous cell carcinoma by clinical and pathologic examination and to discuss their molecular mechanism

키워드
Oral cancerMultiple primaπ squamous cell carcinomaField cancerization
저자
  • 차충민(연세대학교 치과대학 구강병리학교실, 구강종양연구소, BK21 의과학사업단) | Zhong-Min Che
  • 김현실(연세대학교 치과대학 구강병리학교실, 구강종양연구소, BK21 의과학사업단) | Hyun-SiI Kim
  • 김태규(연세대학교 치과대학 구강병리학교실, 구강종양연구소, BK21 의과학사업단) | Tae-Kyu Kim
  • 차인호(연세대학교 치과대학 구강악안면외과학교실) | In-Ho Cha
  • 육종인(연세대학교 치과대학 구강병리학교실, 구강종양연구소, BK21 의과학사업단) | Jong-In Yook
  • 김진(연세대학교 치과대학 구강병리학교실, 구강종양연구소, BK21 의과학사업단) | Jin Kim