KOREASCHOLAR

Al에 의한 어류의 난황단백질 합성 억제 영향 Aluminium Interfere with Vitellogenesis in the Estradiol-17β-Administered Immature Rockfish, Sebastes schlegeli

황운기, 허승, 최옥인, 안경호, 박종수
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해양환경안전학회 학술대회 논문집
2010년도 (사)해양환경안전학회 추계학술발표회 논문집 (2010.11)
pp.235-241
해양환경안전학회 (The Korean Society Of Marine Environment & Safety)
Abstract

E ffe ct of aluminum (al) on the plasma vite llogenin (VTG) , alkaline-labile phosphorus (ALP P ) , Calcium (Ca) , glutamate pyruvate transaminase (GP T) and hepatosomatic index (H SI ) we re examined in the e stradiol-17β (E 2)-administe red immature rockfish, Sebaste s schlege li. F ish we re intrape r itone ally inje cted with E 2 (5 ㎎/㎏ body we ight (B .W.) ) and/ or Al (0, 0.1, 1, 5 and 10 ㎎/㎏ B .W.) and then plasma we re extracted at 7 days. Thick VTG band was de te cted at a mole cularwe ight position of about 170 kD a in SD S-P AGE using the plasma of E 2-administe red rockfish. This band was reduced by the administration of Al to rockfish. Al reduced the concentrations of ALP P and Ca in a concentration-dependent way and a significant reduction occur red at Al concentrations gre ate r than 5 ㎎/㎏ and 10 ㎎/㎏, re spe ctive ly. The concentration of GP T was incre ased in concentration-dependent way at all the group of Al-administe red rockfish. H SI was reduced in a concentration-dependent way. The se re sults sugge st that Al inte r fe re with E 2-induced vite llogene sis by be ing toxic to hepatocyte .

Author
  • 황운기(서해수산연구소) | Un-Gi Hwang (West Sea Fisheries Research Institute /WSFRI, Incheon 400-420, Korea)
  • 허승(서해수산연구소) | Seung Heo (West Sea Fisheries Research Institute /WSFRI, Incheon 400-420, Korea)
  • 최옥인(서해수산연구소) | Ok-In Choi (West Sea Fisheries Research Institute /WSFRI, Incheon 400-420, Korea)
  • 안경호(서해수산연구소) | Kyoung-Ho An (West Sea Fisheries Research Institute /WSFRI, Incheon 400-420, Korea)
  • 박종수(서해수산연구소) | Jong-Soo Park (West Sea Fisheries Research Institute /WSFRI, Incheon 400-420, Korea)