Lipomas are the most common benign mesenchymal tumors composed of mature adipocytes. They are usually slow-growing, soft and asymptomatic masses. Angiolipomas are rare benign soft tissue tumors that are distinguished from common lipomas by a marked degree of vascularization. The diagnosis and prognosis of angiolipomas are based entirely on the findings of histological evaluations. Angiolipoma, showing characteristics of both lipoma and hemangioma, usually develop in the trunk and extremities, and rarely arise in the head and neck region. Angiolipoma of the cheek is very rare. This report presents the clinical and histopathological features of infiltrating angiolipoma excised from the cheek.