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구강저와 하악골에 발생한 기저양 편평세포암종: 증례보고 Basaloid Squamous Cell Carcinoma at the Floor of the Mouth and Mandible: A Case Report

이준상, 김욱규, 황대석, 이준호, 최홍석, 최나래, 유미현, 김규천
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  • URLhttp://db.koreascholar.com/Article/Detail/383511
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대한구강악안면병리학회지
제43권 제5호 (2019.10)
pp.197-202
대한구강악안면병리학회 (Korean Academy Of Oral And Maxillofacial Pathology)
초록

Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma arising in various anatomical sites. This article describes a case history of BSCC of the floor of mouth with mandibular involvement, and further discusses the appropriate management of such case with reference to the literature review. A 52-year-old male patient was referred to our clinic from another university hospital. Segmental mandibulectomy with supraomohyoid neck dissection and mandible reconstruction with left fibular free flap under general anesthesia was performed, followed by radiotherapy. Histopathological examination on the tumor lesion revealed features of squamous cell carcinoma with comedo-type necrosis. A diagnosis of BSCC was given by the oral pathology specialist. Basaloid squamous cell carcinoma (BSCC) is a biphasic variant of SCC with both basaloid and squamous cell histology. A recent report showed that there is no significant difference in the prognosis. Due to the lack of accumulated research, close follow-up and continuous research are deemed necessary. Treatment that focuses on the stage of the tumor is appropriate. A periodic follow-up observation is also very important due to the occurrence of distant metastasis to the lungs.

키워드
Basaloid squamous cell carcinomaSegmental mandibulectomyFibular free flap
목차

Ⅰ. INTRODUCTION
Ⅱ. MATERIALS and METHODS
Ⅲ. RESULTS and DISCUSSION
REFERENCES
저자
  • 이준상(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Jun-Sang Lee (Department of Oral and Maxillofacial Surgery, School of Dentistry)
  • 김욱규(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Uk-Kyu Kim (Department of Oral and Maxillofacial Surgery, School of Dentistry) Correspondence
  • 황대석(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Dae-Seok Hwang (Department of Oral and Maxillofacial Surgery, School of Dentistry)
  • 이준호(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Jun-Ho Lee (Department of Oral and Maxillofacial Surgery, School of Dentistry)
  • 최홍석(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Hong-Seok Choi (Department of Oral and Maxillofacial Surgery, School of Dentistry)
  • 최나래(부산대학교 치의학전문대학원 구강악안면외과학 교실) | Na-Rae Choi (Department of Oral and Maxillofacial Surgery, School of Dentistry)
  • 유미현(구강병리학 교실 BK21 PLUS, 치의생명과학연구소) | Mi Heon Ryu (Department of Oral Pathology, BK21 PLUS project, Dental and Life Science Institute)
  • 김규천(구강해부학 교실) | Gyoo Cheon Kim (Department of Oral Anatomy, School of Dentistry, Pusan National University)