Zerodur, one of the optical materials, was used for large spherical mirrors in this study. For weight reduction, several types of honeycomb structures were investigated. The finite element simulation was used for deformation and mode analysis. It was revealed that the weight reduction rate and maximum deflection due to the gravity effect vary depending on the honeycomb structures. Additionally, this study highlights the potential of spline-shaped honeycomb structures as an alternative for weight reduction, and triangular honeycomb structures demonstrated the less deformation by the gravity effect. The findings from this study provide valuable insights for designing lightweight and high-performance spherical mirrors in optical systems.