This study investigates the enhancement of crew survivability in armored vehicles, particularly against anti-tank mine threats. Human injury criteria were evaluated according to the STANAG 4569 AEP-55, Volume 2 standard to assess the vehicle’s protective performance. Analyses focused on mitigating tibia compression force, identified as a critical challenge in meeting the survivability requirements. Through parametric simulations, the influence of foam compressive strength and thickness on tibia compression force was investigated. Results demonstrate that increasing both foam compressive strength and thickness effectively delays the dissipation of impact energy, leading to a significant reduction in tibia compression force. These findings provide valuable insights for optimizing the design of armored vehicle structures to enhance crew survivability against mine blasts.