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대요크샤 및 랜드레이스종 근교계통돈의 총산자수와 후보유전자에 대한 다형성과 육종가 간의 연관성 분석

Association and Polymorphism of Porcine Candidate Genes with Breeding Values in Litter Size of Large Yorkshire and Landrace Inbred Lines

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  • URLhttps://db.koreascholar.com/Article/Detail/190976
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한국동물번식학회 (The Korean Society of Animal Reproduction)
초록

The objective of this study was to find out candidate genes associated with litter size trait in pigs of inbred Large Yorkshire and Landrace populations. 86 sows were screened for candidate genotypes along with litter size data recordings. Association of litter size with genotypes of candidate genes were investigated to verify the usefulness of each gene's genotypes as markers for the trait. For the lines of Large Yorkshire, PRLR3 and RBP4 genes were genotyped. Frequency distribution of PRLR3 with genotypes AA, AB and BB were each 0.14, 0.44 and 0.42. And the average litter size by PRLR3 genotypes were 8.83, 10.81 and 10.70 piglets per litter, the average estimated breeding values of which were 0.243, 0.332, 0.365, respectively for AA, AB and BB genotypes. Genotypic frequencies of RBP4 by AA, AB and BB genotypes were 0.10, 0.44 and 0.46. The average litter size by genotypes of RBP4 were 10.40, 10.57 and 10.35 piglets per litter and their corresponding average estimated breeding values were 0.451, 0.353 and 0.261, respectively for genotypes AA, AB and BB. Significance in differences among genotypes were not observed, but B allele of RBP4 seems to be associated with litter size. In Landrace lines, frequencies of RBP4 genotypes, AA, AB and BB were 0.29, 0.55 and 0.16. And the average litter size of these genotypes were 10.50, 11.08 and 11.00 piglets per litter. The corresponding averages of estimated breeding values of each genotypes were 0.172, 0.135 and 0.104. In Landrace lines, allele A was more likely to be associated with litter size, even if differences among average litter size were not significant. We conclude that genotyping of two candidate genes is a helpful tool to identify genetic potentials of litter size in pigs.

목차
ABSTRACT   서론   재료 및 방법    공시재료    Genomic DNA 정제    DNA 증폭 및 RFLP    육종가 추정 및 통계 분석   결과 및 고찰   요약   인용문헌
저자
  • 김명직(농촌진흥청 국립축산과학원) | Myung Jick Kim
  • 조규호(농촌진흥청 국립축산과학원) | Kyu Ho Cho
  • 김두완(농촌진흥청 국립축산과학원) | Doo Wan Kim
  • 소경민(농촌진흥청 국립축산과학원) | Kyung Min So
  • 최봉환(농촌진흥청 국립축산과학원) | Bong Hwan Choi
  • 김인철(농촌진흥청 국립축산과학원) | In Cheul Kim Corresponding author