Inhibitory Effects of Chinese Medicinal Plants on the Platelet-Activating Factor (PAF) Receptor Binding
15종의 항어혈성 중국 약용식물의 추출물에 대하여 PAF 수용체 결합 억제활성을 검색한 결과 4종의 약용식물, Campsis grandiflora, Dalbergia odorifera, Zanthoxylum nitidum, Vaccaria segetalis에서 50% 이상의 강한 PAF 결합 저해 활성이 나타났다.
Methanolic extracts of fifteen Chinese medicinal plants were screened for platelet-activating factor (PAF) receptor binding inhibitory activity using rabbit platelet. Campsis grandiflora, Dalbergia odorifera, Vaccaria segetalis and Zanthoxylum nitidum showed significant inhibitory effects on the platelet-activating factor (PAF) receptor binding. Campsis grandiflora, Dalbergia odorifera, Vaccaria segetalis and Zanthoxylum nitidum inhibited 52%, 56%, 70%, and 66% respectively at the concentration of 0.2 mg/ml.