논문 상세보기

Molecular and Cellular Basis of Altered Environmental Toxin susceptibilities in the Drosophila DJ-1 mutants for the familial Parkinson’s disease model

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/312976
모든 회원에게 무료로 제공됩니다.
한국응용곤충학회 (Korean Society Of Applied Entomology)
초록

Exposure to several common acting through oxidation stress environmental toxins has been shown to be associated with Parkinson’s disease (PD). One recently identified inherited Parkinson’s disease (PD) gene, DJ-1, may have a role in protection from oxidative stress, thus potentially linking a genetic cause with critical environmental risk factors [1]. In the present study, initially we assessed the antioxidant activity of Silk Worm Powder (SWP) in selected chemical systems and further explored the efficacy of SWP in Drosophila lacking DJ-1 function (This work was carried out with the support of the Cooperative Research Program for Agriculture Science & Technology Development (Project title: Elucidation the health improvement effects of boiled silk worm larvae, Project No: PJ01082801) Rural Development Administration).

저자
  • Ngan vi Tran(Department of Biomedical Gerontology, Graduate School of Hallym University, Ilsong Institute of Life Science, Hallym University)
  • Young Ho Koh(Department of Biomedical Gerontology, Graduate School of Hallym University, Ilsong Institute of Life Science, Hallym University)