Integrin is a heterodimer protein that locates on cell membrane to interact with neighboring cells or extracellular matrix. A transcriptome analysis of the brassica leaf beetle, Phaedon brassicae, midgut identified both α and β subunits of integrin. RNA interference of β subunit genes significantly impaired survival of both larvae and adults of P. brassicae. A recombinant bacteria expressing double-stranded RNA specific to β integrin of P. brassicae were constructed and showed significant oral toxicities.

• Yonggyun Kim(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
• Youngjin Park(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
• Md Sadekuzzaman(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
• Eunseong Kim(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)