Effects of Oil type on the Stability of Oil-in-Water Lipid Nanoemulsion

Seung-Jun Lee; Sa Ra Han; Jae Hyun Jeong; Jong-Duk Kim

논문 상세보기

Effects of Oil type on the Stability of Oil-in-Water Lipid Nanoemulsion KCI 등재

Seung-Jun Lee, Sa Ra Han, Jae Hyun Jeong, Jong-Duk Kim

언어ENG
URLhttps://db.koreascholar.com/Article/Detail/327667

구독 기관 인증 시 무료 이용이 가능합니다. 4,000원

한국응용과학기술학회지 (The Korean Society of Applied Science and Technology)

Vol.33 No.4 (2016.12)
pp.667-675

한국응용과학기술학회(구 한국유화학회) (The Korean Society of Applied Science and Technology (KSAST))

초록

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

키워드

Lipid Nanoemulsion Microfluidizer Transdermal delivery Arbutin

저자

Seung-Jun Lee(Department of Chemical & Biomolecular Eng., KAIST, 291, Daejeon, 34141, Republic of Korea)
Sa Ra Han(Department of Chemical Engineering, Soongsil University, Seoul, 06978, Republic of Korea)
Jae Hyun Jeong(Department of Chemical Engineering, Soongsil University, Seoul, 06978, Republic of Korea) Corresponding author
Jong-Duk Kim(Department of Chemical & Biomolecular Eng., KAIST, 291, Daejeon, 34141, Republic of Korea)

같은 권호 다른 논문