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단양쑥부쟁이에 함유된 Caffeoylquinic Acid의 HPLC 분석과 Peroxynitrite 소거효과 KCI 등재

HPLC Analysis on the Cafffeoylquinic Acids of Aster altaicus var. uchiyamae Kitamura and Peroxynitrite-scavenging Effect

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한국자원식물학회지 (Korean journal of plant resources)
한국자원식물학회 (The Plant Resources Society Of Korea)
초록

Five caffeoylquinic acids of Aster altaicus var. uchiyamae Kitamura (Compositae) leaves were identified using standard compounds by HPLC and determined as follows: 3,4-di-O-caffeoylquinic acid (4.92 ± 0.06 ㎎/g dried weight), 3,5-di-O-caffeoylquinic acid (3.95 ± 0.13 ㎎/g), 4,5-di-O-caffeoylquinic acid (1.39 ± 0.10 ㎎/g), 5-O-caffeoylquinic acid (chlorogenic acid, 8.05 ± 0.21 ㎎/g), 3-O-caffeoylquinic acid (4.97 ± 0.18 ㎎/g). The total content of five caffeoylquinic acids were calculated as 26.73 ± 0.26 ㎎/g dried weight while the percentage of the five compounds in the MeOH extract was calculated as 25.22 ± 0.25%. The IC50 value of the MeOH extract scavenging peroxynitrite (ONOO - ) was shown as 5.16 ± 0.15 ㎍/㎖.

저자
  • 임상철(상지대학교 친환경식물학부) | Sang-Cheol Lim (Division of Environment-Friendly Botanical Resources, Sangji University) Corresponding author
  • 박희준(상지대학교 제약공학과) | Hee-Juhn Park (Department of Pharmaceutical Engineering, Sangji University)