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죽염의 특성 분석과 항위궤양효과 KCI 등재

Characterization and Anti - Gastric Ulcer Activity of Bamboo Salt

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한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
한국식품위생안전성학회 (Korean Society of Food Hygiene and Safety)
초록

Bamboo salt has been used as a traditional remedy for gastric ulcer and gastro-intestinal disorders. It is produced by baking the salt packed in bamboo cylinder nine times under the fire of pine tree. Three of commercially available bamboo salt products (bamboo salt A, B, and C) were characterized by qualitative and quantitative analyses using inductively coupled plasma (ICP) spectrometer, ion chromatograph (IC), X-ray diffractometer (XRD), and electron microscope (EM). Compared with crude salt, the contents of iron, silicon, potassium, and phosphate in the bamboo salt products were higher whereas the sulfate content was lower. Water-insoluble fraction of bamboo salts contained the following compounds; MgO, SiO₂, Mg₂SiO₄, and CaMgSiO₄. The study on the microscopic structures of the bamboo salts were shown to have smooth surface and fused shape compared with crude salt. Among the three bamboo salt products, product A was used to test a possible inhibitory effect on gastric acid secretion. Each test material (bamboo salt A, crude salt, and reagent-grade NaCl) was given orally to Sprague-Dawley rats at doses of 0.2, 1.0, and 2.0 g/kg for 28 days before pyrolus ligation. Twenty four hours after the last administration of the test materials, volume, pH, total acidity, and pepsin activity of gastric juice were measured by the Shay-ligation method. No significant differences were observed in the secretion of gastric acid between treated groups (bamboo salt-, crude salt- and reagent-grade NaCl-treated groups) and control group (distilled water-treated group). This result demonstrated that bamboo salt did not exert anti-ulcer activities in experimental animals used in the present study.

저자
  • 김승희(식품의약품안전청 국립독성연구소 약리부) | Seung Hee Kim
  • 강석연(식품의약품안전청 국립독성연구소 약리부) | Seog Youn Kang
  • 정기경(식품의약품안전청 국립독성연구소 약리부) | Ki Kyung Jung
  • 김태균(식품의약품안전청 국립독성연구소 약리부) | Tae Gyun Kim
  • 한형미(식품의약품안전청 국립독성연구소 약리부) | Hyung-Mee Han
  • 류항묵(식품의약품안전청 국립독성연구소 약리부) | Hang Mook Rheu
  • 문애리(덕성여자대학교 약학대학) | Aree Moon