A simple and sensitive analytical method was developed using gas chromatography with electron capture detector (GC-ECD) and gas chromatography-mass spectrometry (GC-MS) for determination of Picoxystrobin in agricultural products (apple, hulled rice, mushroom, pepper, soybean, and mandarin). Picoxystrobin residues were extracted with acetonitrile, partitioned with saline water, and then they were cleaned up on a florisil solid-phase extraction (SPE) cartridge to obtain an extract suitable for analysis by GC-ECD and GC-MS. The method was validated using 6 agricultural product samples spiked with Picoxystrobin at different concentration levels (0.02, 0.05 and 0.5 mg/L). Average recoveries of Picoxystrobin (using each concentration three replicates) ranged 64.0~98.3% with relative standard deviations less than 10%, calibration solutions concentration in the range 0.1~5 mg/L, and limit of detection (LOD) and limit of quantification (LOQ) were 0.005 and 0.02 mg/L, respectively. The result showed that the developed analytical method is suitable for Picoxystrobin determination in agricultural products.

ABSTRACT
 Introduction
 Materials and Methods
  Standards, Reagents, and Samples
  Stock and working standard solution
  Extraction procedure
  Purification procedure
  Chromatic Separation Parameters
  Method Validation
 Results and Discussion
  Sample preparation
  Linearity
  Selectivity
  Accuracy and Precision
  Detection and Quantification Limits
 Conclusions
 Acknowledgement
 요 약
 References

• Jung-Ah Do(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA)
• Min-Hye Lee(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA)
• Hyejin Park(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA)
• IL-Hyun Kang(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA)
• Kisung Kwon(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA)
• Jae-Ho Oh(Food Chemical Residues Division, National Institute of Food and Drug Safety Evaluation, KFDA) Correspondence to