We present the results of one-dimensional numerical simulations of SNR evolution in the inhomogeneous medium considering the effects of the evaporation of the cloud and the thermal conduction. We have included the effects of changing evaporation rate as a function of cloud size and the ambient temperature so that the clouds could be evaporated completely before they reach the center of the SNR. The heat conduction markedly changes the density distribution in the remnant interior. To explain the observed morphologies of the centrally peaked X-ray SNRs(for example W44), the maximal thermal conduction is required. However, this is unlikely due to the magnetic field and the turbulent motion. The effects of the evaporation of the cloud and the thermal conduction described here may explain the class of remnants observed to have centrally peaked X-ray emmision.