In other to elucidate the neuroprotective effects of Haeahwan on oxidant-induced neurotoxicity in cultured rat spinal motor neurons, the colorimetric assay such as MTT, NR, LDH, Lipid peroxidation was also carried out after cultured spinal motor neurons from neonatal rat were treated with the medium containing various concentrations of Methylmercuric chloride(MMC) for 8 hours. In addition, the protective effect of Haeahwan water extract extracts on the neurotoxicity induced by oxygen radicals was examined in these cultures. The results were as follows : 1.Survival rate of cultured spinal motor neurons were remarkably decreased by MMC depending on different kinds of concentrations. 2.NR50 of MMC as 50μM. 3.Haeahwan water extract inhibited significantly the increase in LDH activities induced by MMC.

• 朴成哲(圓光大學校韓醫科大學生理學敎室) | 박성철
• 金炳憲(圓光大學校韓醫科大學生理學敎室) | 김병헌
• 李晋承(圓光大學校韓醫科大學生理學敎室) | 이진승
• 崔圭善(圓光大學校韓醫科大學生理學敎室) | 최규선
• 許珍榮(圓光大學校韓醫科大學生理學敎室) | 허진영
• 林楊義(圓光大學校韓醫科大學生理學敎室) | 임양의
• 成恩慶(圓光大學校韓醫科大學生理學敎室) | 성은경
• 李寬炯(圓光大學校韓醫科大學生理學敎室) | 이관형
• 柳道坤(圓光大學校韓醫科大學生理學敎室) | 류도곤