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Genome-wide Association Study Identifies Positional Candidate Genes Affecting Carcass Weight Trait in Pigs

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농업생명과학연구 (Journal of Agriculture & Life Science)
경상대학교 농업생명과학연구원 (Institute of Agriculture & Life Science, Gyeongsang National University)
초록

In the swine industry, growth related traits are important economic traits directly linked to profitability. Representative growth traits include daily gain, back fat thickness, and carcass weight. This study was conducted to search for positional candidate genes associated with the carcass weight through a genome-wide association study(GWAS) using suggestive levels of statistical thresholds in pigs. As a result of the genome-wide analysis of the associations with carcass weight, the single nucleotide polymorphism(SNP) markers with suggestive significance were identified in 1 SNP marker on chromosome 2(ALGA0015365) and 1 SNP marker on chromosome 4(ALGA0023678). We could select positional 2 candidate genes, located close to the SNP markers with suggestive significance levels. The SNP markers in adjacent to the 2 genes(LOC100519538, LOC100737583) may provide basic data regarding the marker-assisted selection for the carcass weight trait in pigs.

저자
  • 이재봉(전북대학교 인수공통전염병연구소) | Jae-Bong Lee (Korea Zoonosis Research Institute(KoZRI), Chonbuk National University, Iksan, 54531, Korea)
  • 박희복(농촌진흥청 국립축산과학원) | Hee-Bok Park (Subtropical Animal Experiment Station, National Institute of Animal Science, RDA, Jeju, 63242, Korea)
  • 신준호(경상대학교 응용생명과학부(BK21 plus)) | Jun-Ho Shin (Division of Applied Life Science(BK21 plus), Gyeongsang National University, Jinju, 52828, Korea)
  • 유채경(경상대학교 부속 농업생명과학연구원) | Chae-Kyoung Yoo (Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 52828, Korea)
  • 손난주(경상대학교 응용생명과학부(BK21 plus)) | Nan-Ju Son (Division of Applied Life Science(BK21 plus), Gyeongsang National University, Jinju, 52828, Korea)
  • 김희성(경상대학교 응용생명과학부(BK21 plus)) | Hee-Sung Kim (Division of Applied Life Science(BK21 plus), Gyeongsang National University, Jinju, 52828, Korea)
  • 조인철(농촌진흥청 국립축산과학원) | In-Cheol Cho (Subtropical Animal Experiment Station, National Institute of Animal Science, RDA, Jeju, 63242, Korea)
  • 임현태(경상대학교 부속 농업생명과학연구원) | Hyun-Tae Lim (Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 52828, Korea) Corresponding author