In this study, the DPPH free radical scavenging activity, antimicrobial effects, growth inhibition and cytotoxicity of herb extracts were determined to screen alternative antibiotics. Hot water extracts of 10 species herbs (Origanum vulgare, Monarda didyma, Echinacea purpurea, Ocimum basilicum, Mentha piperita, Melissa officinalis, Thymus vulgaris, Stevia rebaudiana, Rosmarinus officinalis, Matricaria recutica) were used. DPPH free radical scavenging activity of all herb extracts was ranged from 31.4-49.9%, and significantly great activties were found at Rosmarinus officinalis, Origanum vulgare and Matricaria recutica (P<0.05). Hot water extracts of monarda didyma, origanum vulgare, thymus vulgaris and rosmarinus officinalis showed greater antimicrobial activities compared to others. Additionally, those four extracts represented relatively low cytotoxicity compared to others. As a result, it was found that Origanum vulgare and Rosmarinus officinalis which possessed great antioxidant and antimicrobial activity with less cytotoxicity. So these two herb extracts can be used as an alternative of antibiotics for organic farming.

Ⅰ. 서 론
 Ⅱ. 재료 및 방법
  1. 시료 제조
  2. 항산화 활성
  3. 허브 추출물의 항균활성 측정
  4. 허브 추출물의 세포독성 측정
  5. 통계분석
 Ⅲ. 결과 및 고찰
  1. 항산화 활성 비교
  2. 항균 활성 비교
  3. 세포독성 평가
 Ⅳ. 적 요
 References

• 강다래(전북대학교 농업생명과학대학 동물생명공학과) | Kang, Da-Rae
• 심관섭(전북대학교 농업생명과학대학 동물생명공학과) | Shim, Kwan-Seob
• 최호성(전북대학교 농업생명과학대학 동물생명공학과) | Choe, Ho-Sung
• 나종삼(전북대학교 농업생명과학대학 동물생명공학과) | Na, Chong-Sam Corresponding author