논문 상세보기
pp.10-15
The leaves and stems of Dendropanax morbiferus were separated from organic solvents with methanol. The organic solvent fractions were fractionated with dichloromethane, ethyl acetate and butanol according to the systematic fractionation method. Oxidation in the body induces aging, and antioxidant activity has attracted the attention of many people as a preventive component to suppress negative reactions in the body. To investigate the antioxidant activity of Dendropanax morbiferus were subjected to DPPH free radical assay. In addition, acetyl cholinesterase inhibitions were performed for Alzheimer’s disease as an aging neurological disease. As a result, it was confirmed that the antioxidant effect of DPPH was generally good in the antioxidant test. The ethyl acetate fractions of Dendropanax morbiferus stems and leaves were IC50=30 ㎍/㎖. Acetyl cholinesterase inhibition experiments were carried out at a concentration of 250 ㎍/㎖. Dendropanax morbiferus stems fractions showed dichloromethane fraction of 57.68%, which significantly inhibited the activity of acetyl cholinesterase.
재료 및 방법
식물 재료 및 시료의 추출, 분획
박층크로마토그래피와 발색법을 이용한 알칼로이드 성분군의 동정
DPPH assay를 이용한 항산화 활성 분석
Acetylcholinesterase 저해 활성 측정
결과 및 고찰
박층크로마토그래피와 발색법을 이용한 알칼로이드 성분군의 동정결과
DPPH assay를 이용한 항산화 활성
Acetylcholinesterase 저해 활성 측정
적 요
사 사
References
