In this study, the effects of four major river project and Kumho River, second biggest branch of Nakdong River, were investigated to provide basic data for proper management of Nakdong River’s water quality. Daily sampling processes at three different points, Munsanri (the upper side of Kangjung-Koryung weir), Kangchang (the outlet of the Kumho River) and Samunjin (the lower side of Kangjung-Koryung weir and junction of Kumho River and Nakdong River), were conducted from May 1st 2011 to Sep. 4th 2011. Water samples were analyzed for nine factors, DO, BOD, COD, T-N, T-P, pH, turbidity, SS, and coliform. As demonstrated by the results, concentrations of BOD, T-N, T-P and coliform at Nakdong River were affected by water quality of Kumho River while SS and turbidity were affected by constructions for Kangjung-Koryung weir. Further studies, for example, affects of wastewater treatment facilities, should be followed.