Clostridium perfringens (C. perfringens) may cause diarrhea and enterotoxemia in adult and young livestock, leading to problems in the production and management of farms. Four hundred fecal samples were collected from 25 goat farms located in Gyeongsangbuk-do Province in the Republic of Korea. Sixteen C. perfringens strains were isolates from fecal samples, and the isolates were identified as type A (n=11) and type D (n=5). Additionally, α- and ε-toxin genes were detected in 16 and 5 strains by PCR, respectively, and the enterotoxin gene was presented in 2 strains. The antibiotic susceptibility test was performed using the disk diffusion method and E-test method. In the disk diffusion method, ampicillin (n=16) and chloramphenicol (n=15) were highly susceptible to 16 C. perfringens isolates. In the E-test method, ampicillin, amoxicillin, amoxicillin/clavulanic acid and meropenem were susceptible to more than 14 of 16 C. perfringens isolates. This study indicates that administration of antibiotics such as ampicillin, amoxicillin/clavulanic acid and meropenem can prevent and treat C. perfringens infections in goats.

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
 RESULTS
 DISCUSSION
 REFERENCES

• Jun-Ho Kim(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Gyeongbuk Veterinary Service Laboratory)
• Jeong-Hwa Kim(Gyeongbuk Veterinary Service Laboratory)
• Young-Hoan Kim(Gyeongbuk Veterinary Service Laboratory)
• Kwang-Hyun Cho(Gyeongbuk Veterinary Service Laboratory)
• Sang Yoon Nam(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
• Hu-Jang Lee(College of Veterinary Medicine and Institute of Animal Medicine, Gyeongsang National University) Corresponding Author
• Beom Jun Lee(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Corresponding Author