韓國食生活文化學會誌 제34권 제5호 (p.645-650)

큰달맞이꽃 지상부 추출물의 피부 관련 생리활성 효과

The Skin-Related Biological Activities of Aerially Extract of Oenothera lamarckiana
키워드 :
Oenothera lamarckiana,anti-oxidation,anti-aging,anti-bacterial activity

목차

Abstract
I. 서 론
II. 연구 내용 및 방법
III. 결과 및 고찰
IV. 요약 및 결론
References

초록

Skin plays important roles in protecting the internal organs from the chemical-biological risk factors and ultraviolet light. Exposure to the chemical and biological stimuli has a detrimental effect on skin's structure and physiological regulation. Therefore, much attention has been paid to natural products that show biological activities such as anti-oxidation, anti-aging and anti-bacterial activities. In this study, we investigated the skin-related biological activities of Oenothera lamarckiana aerial part extract. The extract contained 229.35 mg TAE (tannic acid equivalents)/g total polyphenolic compounds and the extract showed relative high antioxidant activity (SC50 value: 8.52 μg/mL). The IC50 value against tyrosinase and elastase were 307.94 and 181.51 μg/mL, respectively. This suggested that O. lamarckiana can be applied to whiten skin and slow the aging of skin. O. lamarckiana extract showed a growth inhibitory effect on Staphylococcu epidermidis (minimum inhibitory concentration: 250 μg/mL). Interestingly, O. lamarckiana extract showed no inhibitory effect on Pseudomonas aeruginosa on the paper disc assay. Yet the extract inhibited the growth of Pseudomonas aeruginosa on the broth dilution assay in a dose-dependent manners. Taken together, O. lamarckiana could have good potential for development as an additive in the cosmetic industry.