한국식품영양학회지 Vol. 33 No. 3 (p.317-321)

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호박고구마 물 추출물 투여가 마우스의 비장세포와 사이토카인의 분비량에 미치는 영향

Effect of Pumpkin Sweet Potato (Ipomoea batas L.) Water Extracts on Mouse Spleen and Cytokine Cell Activation
키워드 :
splenocytes proliferation,pumpkin sweet potato,cytokine production

목차

Abstract
서 론
재료 및 방법
   1. 시료 및 실험동물
   2. 마우스 비장세포의 분리, 배양 및 측정
   3. 사이토카인(IL-1β, IFN-γ, TNF-α) 분비량 측정
   4. 통계처리
결과 및 고찰
   1. 호박고구마 물 추출물이 마우스 비장세포 활성효과-In vitro 실험
   2. 호박 고구마 물 추출물이 사이토카인 분비량에 미치는영향
요약 및 결론
References

초록

Pumpkin sweet potato (Ipomoea batas L.) has been known as a traditional remedy and food source, not only in South Korea but worldwide. It is rich in fiber, potassium, vitamin C, and other minerals and vitamins, making it a nutritional food loved by many. showed that pumpkin sweet potato had antioxidant biological effects. The in vitro study showed that both splenocytes and cytokine production byactivated peritoneal macrophages increased when water extracts were supplemented at 100 and 250 μL/mL. Notably, the production of IL-1β, TNF-α, and IFN-γ by splenocytes was significantly increased at 100 μL/mL. The results suggest that supplementation with pumpkin sweet potato (Ipomoea batas L.) water extract may enhance immune function by stimulating splenocyte proliferation and improving cytokine production, activating macrophages in vitro.