본 연구는 한국근로자를 대상으로 하여 성장욕구가 직무열의와 직무탈진에 영향을 미치는지 조사하였 다. 이와 더불어 부정적 정서조절과 내적 동기가 이들 변수 간의 관계에 영향을 미치는지에 대해서도 검증하였다. 본 연구를 위해 한국의 제조기업에 근무하는 244명의 근로자에게 자기보고식 설문조사를 실시 하였다. 연구결과, 직무열의와 직무탈진에 대한 성장욕구의 직접 효과는 없는 것으로 나타났다. 그러나 이들 변수들 간의 관계는 부정적 정서조절과 내적 동기의 매개역할에 의해 강화되는 것으로 나타났다. 즉 성장욕구와 직무열의의 관계에 대해 부정적 정서조절과 내적 동기는 매개효과를 가졌으며, 성장욕구와 직무탈진의 관계에 부정적 정서조절이 매개효과를 가졌다. 이 결과를 통해 본 연구는 성장욕구와 직무 열의, 직무탈진의 관계에 대한 부정적 정서조절 및 내적 동기와 같은 심리적 특성의 중요성을 확인하였다.

The development of drugs from natural plant sources is at growing interest due to the limitations of chemical drugs in terms of side effects and cost-effective factors of natural medicines. Among the various components contained in natural plant materials, flavonoids are of increasing interest because of their extended biological benefits. Flavonoids are classified into various types according to their structure and possess different activities depending on the structure. In this study, the flavonoids contained in Artemisia, native to Korea were examined and reviewed. HPLC chromatograms of three Artemisia species (Artemisia annua L., Artemisia iwayomogi and Artemisia argyi H.) were examined from published sources and their component analysis by MS data were summarized. The various flavonoids of Artemisia were classified into 12 types according to the main structure, and 10 flavonoids based on various activities were examined. The 10 flavonoids were identified as quercetin, kaempferol, rhamnetin, diosmetin, luteolin, methoxyflavone, catechin, apigenin, malvidin and genkwanin with extensive reported studies till date. The ten flavonoids examined have been reported to be effective in preventing and treating various diseases and exhibit activities such as anti-cancer, anti-inflammatory, antioxidant, antiviral, anti-obesity, anti-diabetic and anti-Alzheimer. The collective results from the reported studies suggest that the three types of Korean native Artemisia, contains various flavonoids with beneficial activities and may have therapeutic effects against diseases.

The Dynamic Vehicle Routing Problem (DVRP) involves a combinatorial optimization problem where new customer demands become known over time, and old routes must be reconfigured to generate new routes while executing the current solution. We consider the high level of dynamism problem. An application of highly dynamic DVRP is the ambulance service where a patient contacts the service center, followed by an evaluation of case severity, and a visit by a practitioner/ ambulance is scheduled accordingly. This paper considers a variant of the DVRP and proposes a decentralized algorithm in which collaborators (Depot and Vehicle), both have only partial information about the entire system. The DVRP is modeled as a periodic re optimization of VRP using the proposed decentralized algorithm where collaborators exchange local information to achieve the best global objective for the current state of the system. We assume the existence of a dispatcher e.g., headquarter of the company who can communicate to vehicles in order to gather information and assigns the new visits to them. The effectiveness of the proposed decentralized coordination algorithm is further evaluated using benchmark data given in literature. The results show that the proposed method performed better than the compared algorithms which utilize the centralized coordination in 12 out of 21 benchmark problems.

This study aimed to examine the effect of a mild elevation in serum cholesterol level in a porcine coronary overstretch restenosis model using a balloon angioplasty catheter or drug-eluting coronary stent. Pigs were divided into two groups and were fed a commercial normal diet (CND, n = 4) or a high-fat diet (HFD, n = 4) for 5 weeks. Coronary overstretch injury by balloon angioplasty or stent implantation was induced in the left anterior descending and left circumflex artery after 1 week of feeding. Histopathological analysis was performed at 4 weeks after coronary injury. During the experiment, the total cholesterol level in the HFD group increased by approximately 44.9% (from 65.9 ± 3.21 mg/dL at baseline to 95.5 ± 9.94 mg/dL at 5 weeks). The lumen area in the CND group was reduced in comparison with that in the HFD group after balloon angioplasty. After stent implantation, the injury score showed no significant difference. There were significant differences in the neointimal area (2.7 ± 0.33 mm2 in the CND group vs. 3.3 ± 0.34 mm2 in the HFD group, p<0.05), lumen area (2.6 ± 0.54 mm2 in the CND group vs. 2.0 ± 0.33 mm2 in the HFD group, p<0.05), and percent area stenosis (52.0 ± 7.96% in the CND group vs. 62.4 ± 5.15% in the HFD group, p<0.05). Body weight change was not different between the two groups. Increased serum cholesterol level activated vascular smooth muscle cell proliferation in the porcine coronary overstretch model.