본 연구에서는 원예치료가 지적장애 청소년의 자아존중감과 정서지능에 미치는 영향에 대해 알아보고자 하였다. 일반 고등학교 특수학급의 지적장애 학생5명을 대상으로 원예치료 프로그램을 실시하기 전과 후의 자아존중감과 정서지능을 평가하였다. 원예치료는 지적장애 청소년에게 다양한 원예활동을 통하여 본인의 생각과 느낀 점들을 잘 표현하게 하고 어려운 작업들도 할 수 있다는 자신감으로 쉽게 포기하지 않고 다시 시도하여 더 큰 만족감을 경험할 수 있게 하였다. 또한 식물에게 자신의 감정이입을 하여 다른 사람의 감정을 이해하고 수용하며 스스로의 감정을 조절할 수 있게 되어 원예치료가 지적장애 청소년의 자아존중감과 정서지능 향상에 효과적임을 알 수 있었다

The study was done to investigate the effects of the extracts from the different parts of Lythrum salicaria (LS) on liver protective activities in chronically alcohol-treated rats. SD male rats except normal animals were administrated with alcohol (30ml of 30%~40% ethanol/kg/day) and the extracts (300 mg/kg/day) for 10 weeks. Chronic alcohol administration decreased body weight, high density lipoprotein (HDL)-cholesterol and the reduced form-glutathione (GSH), whereas increased the ethanol content, glutamic-oxaloacetic transaminase (GOT), total cholesterol, low density lipoprotein (LDL)- cholesterol, triglyceride in blood/serum and the ratio of the oxidized form of glutathione (GSSG) and total GSH (GSSG/total GSH) in liver tissue. Groups treated with the extracts of leaf, root and stem, showed decrease in GOT, total cholesterol and GSSG/total GSH and increase in hepatic aldehyde dehydrogenase (ALDH), total GSH and serum albumin. Administration with the root extract of LS decreased blood ethanol content compared with the other part extracts. But, serum triglyceride values in rats treated with root and stem extract were higher than that of the negative control animals. Flower extract-fed group showed decrease in body weight and serum triglyceride, but increase in the ratio of GOT and glutamic-pyruvic transaminase (GPT), and GSSG/total GSH. From the results, we conclude that the extracts of root and leaf among the plant parts of LS might be useful for the amelioration of the chronic alcohol-induced liver demage of rat.

The study was conducted to investigate candidate materials as anti-inflammation agent from plant resources. Activities of 33 plant parts extracts with the final concentration of 5μg/ml were evaluated on the several inflammation-related markers such as the release of proinflammatoty cytokine [tumor necrosis factor-alpha (TNF-α) & interleukin-6 (IL-6)], nitric oxide (NO), the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and inhibitor of nuclear factor kappa-B alpha (Ik-Bα) in lipopolysaccharide (LPS)-treated RAW 264.7 cells. The extracts in the final concentration of 10 μg/ml were also screened on peroxynitrite (ONOO-) scavenging activity. Eleven extracts selected from the screening assay were verified on the inhibition activity on peroxynitrite and total reactive species oxygen (ROS) in the several concentrations. As results, Alpinia officinarum Hance (rhizome), Inula britannica var. chinensis Regel (flower), Ulmus arvifolia Jacq (trunk peel) and Aster scaber Thunb. (aerial part) showed comparatively potent anti-inflammatory activities in vitro cells or chemical level systems, and then these four plant parts should be studied on the antiinflammatory mechanism by further studies.

본 연구는 노인 주간보호 시설을 이용하고 있는 70세 이상의 여성 노인 9명을 대상으로 6월 19일부터 8 월 28일까지 일주일에 1회 원예치료 프로그램을 실시하여 우울과 자아존중감을 어떠한 영향을 미치는 가를 알아보고자 실시하였다. 원예치료 프로그램의 효과를 알아보기 위해 프로그램 전과 후에 노인 우울 측정지와 자아존중감 측정지를 이용하여 평가하였다. 또한 매회기마다 대상자들을 관찰하여 평가하였다. 노인 우울을 측정한 결과, 워예치료 프로그램 실시 전보다 실시 후 8명의 대상자가 우울이 감소하였고, 1명은 변화가 없었다. 우울 측정치는 프로그램 실시 전 평균 22.3점에서 실시 후 17.3점으로 감소하였고, 통계적으로도 유의성이 나타났다. 원예치료 프로그램 실시 전보다 실시 후 자아존중감은 6명이 향상되었고, 2명은 감소하였다. 전제적으로 프로그램 실시 전 평균 24.1점에서 실시 후 25.8로 향상되었으나, 통계적으로는 5% 신뢰 수준에서 유의성이 없었다. 관찰평가에서 참여성, 집중도, 감정표현, 호응도, 대인관계, 언어소통능력, 자신감, 성취도 등이 프로그램 회기가 진행될수록 향상되었다.

Root extract of Lythrum salicaria reported a hepato-protective effect on CCl4-induced liver toxicity of rat was prepared into fractions such as n-hexane up layer (HA), n-hexane down layer (HB), diethyl ether (E), ethylacetate (EA), n-butanol (B) and water (W). Fractions prepared were tested their activities in vitro and in vivo condition. All of the fractions showed effective antioxidant asctivities on DPPH radical and CuSO4-induced oxidation of human low density lipoprotein and E fraction showed the highest inhibitory effect (98.1% at 50 μg/ml) on linoleic acid autoxidation at 40℃, which was more effective than α-tocopherol (82.4%). Five fractions (H = HA plus HB, E, EA, B, and W, 150 mg/kg/day) were fed into Sprague Dawley, male rats for 4 days, which were intoxicated with intra-peritoneal injection of carbon tetrachloride (1 ml/kg in corn oil) at the 4th day and were sacrificed in 24 hrs. Serum tumor necrosis factor-alpha (TNF-α), a proinflammatory cytokine, elevated with CCl4-intoxication in negative control group (83 pg/ml) was significantly decreased in E fraction-supplemented group (18 pg/ml). Cu, Zn-superoxide dismutase (SOD) activity increased in negative control group (0.12 U/mg protein) was decreased in E fraction (0.07 U/mg protein). From the results, it is suggested that ether fraction from root extract of L. salicaria would be a potent antioxidant candidate for ameliorating liver injury induced by chemical intoxicant.