Correct air diffusion is essential for good air quality, comfortable conditions and energy efficiency in mechanical ventilation system. One general method to improve indoor air quality is to simply increase the ventilation rate. This approach, however, often conflicts with building energy efficiency requirement because conditioning outdoor air to the proper temperature, humidity level count for use as ventilation air consumes energy. Therefore, it is necessary for designers to predict the air movement properly. Successful predictions of room airflow yield such information as velocities and temperature distributions, which are useful to building design and analysis. In this paper, the application of computational fluid dynamic (CFD) techniques to large space design and analysis was investigated by comparing the results of CFD simulations and experimental results.