Human bitter taste-sensing type 2 receptors (hTAS2Rs) are expressed in various human tissues and may be associated with various cell signaling pathways, cell progression, and cell physiology in each tissue. hTAS2Rs can be a potential drug target because it is also expressed in some cancer cells. Xanthorrhizol (XNT) has various biological activities, such as anticancer, antimicrobial, anti-inflammatory, and antioxidant. XNT produces a bitter taste, but the specific hTAS2R activated is unknown, and the hTAS2R-mediated effect of XNT on cancer cells has not been studied. This study discovered the target receptor of XNT among 25 hTAS2Rs and confirmed the possibility of the hTAS2R-mediated inhibition of cancer cell proliferation. XNT activated only one receptor, hTAS2R38 (EC50=1.606±0.021 g/mL), and its activity was inhibited by probenecid, a hTAS2R38 antagonist. When HepG2 and MCF-7 cells were treated with XNT or phenylthiocarbamide (PTC), a known hTAS2R38 agonist, both chemicals inhibited cancer cell proliferation. XNT targets the human bitter taste receptor TAS2R38 and inhibits the proliferation of HepG2 and MCF-7 cells mediated by TAS2R38. This suggests that TAS2R38 may be a new target for disease treatment and a potential new factor for drug development.

Organoleptic parameters such as color, odor, and flavor influence consumer perception of drinking water quality. This study aims to evaluate the taste of the selected bottled and tap water samples using an electronic tongue (E-tongue) instead of a sensory test. Bottled and tap water's mineral components are related to the overall preference for water taste. Contrary to the sensory test, the potentiometric E-tongue method presented in this study distinguishes taste by measuring the mineral components in water, and the data obtained can be statistically analyzed. Eleven bottled water products from various brands and one tap water from I city in Korea were evaluated. The E-tongue data were statistically analyzed using multivariate statistical tools such as hierarchical clustering analysis (HCA), principal component analysis (PCA), and partial least squares discriminant analysis (PLS-DA). The results show that the E-tongue method can clearly distinguish taste discrimination in drinking water differing in water quality based on the ion-related water quality parameters. The water quality parameters that affect taste discrimination were found to be total dissolved solids (TDS), sodium (Na+), calcium (Ca2+), magnesium (Mg2+), sulfate (SO4 2-), chloride (Cl-), potassium (K+) and pH. The distance calculation of HCA was used to quantify the differences between 12 different types of drinking water. The proposed E-tongue method is a practical tool to quantitatively evaluate the differences between samples in water quality items related to the ionic components. It can be helpful in quality control of drinking water.

본고는 BCC 코퍼스를 활용한 중국어 미각어 용례 연구로 미각어 ‘甜’과 ‘苦’에 후 행하는 품사를 중심으로 살펴보고자 한다. 이에 BCC 코퍼스를 활용한 미각어 ‘甜’과 ‘苦’ 각각의 연구 방법과 비교 분석을 통해 연구하고자 한다. 본고는 기존 미각어 연 구에서 볼 수 없었던 방대한 데이터를 활용하여 BCC 코퍼스 내의 코퍼스 분석 도구 를 활용하여 보다 객관적이고 과학적으로 양적인 면에서의 미각어 ‘甜’과 ‘苦’에 후행 하는 용례를 고찰하고자 한다.

This study aimed to examine the possibility of upcycling extracts of Angelica keiskei and Oenanthe javanica juice by-products through comparing enzyme extraction (EE) and complex extraction (CE) methods to increase the extraction yield and flavor of materials. A higher extraction yield was obtained for free amino acid content with EE and CE for A. keiskei and O. javanica juice by-products, respectively, and a higher extraction efficiency was achieved with juice by-products than with extracts prepared from raw materials before juice production. The content of major amino acids varied depending on the extraction method used. When used according to the characteristics of the extract, their use as a functional material was confirmed along with improvement in the flavor of the food. Consistently high extraction yields for organic acid and sugar levels were obtained with CE in A. keiskei and O. javanica juice by-products. The DPPH radical scavenging ability and TPC were consistently high with CE in A. keiskei and O. javanica juice by-products; the increase in extracted content was likely because of the reaction between the ethanol used for CE and the phenolic compounds. However, because the antioxidant capacity of the juice by-product extracts was somewhat lower than that of the extracts from raw materials before juice production, the amount used should be reviewed. The TFC was found to be higher in extracts obtained with EE than with CE for A. keiskei juice by-products; however, no significant difference was observed between EE and CE in the O. javanica juice by-products. Through this study, the taste compounds and antioxidant properties of extracts obtained from juice by-products produced after the production of A. keiskei and O. javanica green juice were analyzed, and the availability of high value-added materials was confirmed. Based on these research results, expanding specific R&D for practical use should be explored.

In this study, the characteristics and taste components of six different oyster mushroom cultivars (Gonji-7ho, Santari, Baekseon, Chunchu, Suhan, and Heuktari) were analyzed and compared. The Heuktari mushroom pileus had the lowest brightness index (32.8) and remained dark (brightness index: 30.5) even after blanching. The moisture content of the mushrooms was approximately 90%. The salinity and sugar contents were highest in Heuktari (5.7% and 7.1%, respectively). Gonji -7ho had the highest contraction rates, with a length contraction rate of 16.4% and thickness contraction rate of 23.9%. The total amino acid content was highest in Heuktari (537.8 mg/100 g), but the glutamine content contributing to umami taste was highest in Santari (59.4 mg/100 g) and the aspartic acid content was highest in Baekseon (33.1 mg/100 g). Among the 5?-nucleotide components, guanosine monophosphate, which enhances umami taste, was highest in Baekseon (0.7 mg/g). Baekseon was also calculated to have the highest umami taste concentration based on amino acid and nucleic acid contents (12.7 g/100 g). The results of this study serve as valuable basic data on the physicochemical characteristics of oyster mushroom cultivars grown in Korea.

To develop customized food products for gastric cancer patients, it is crucial to understand their dietary characteristics and changes in their perception of smell and taste due to their condition. This study conducted in-depth interviews and administered olfactory and gustatory tests on 20 patients with gastric cancer. A control group of 20 healthy, gender and age matched individuals, was included for comparison. Patients reported difficulties in sustaining their appetite, particularly during chemotherapy. This could be attributed to gastrointestinal discomfort and an altered perception of smell and taste. The olfactory test revealed that cancer patients were significantly less sensitive than the control group. Also, a smaller number of participants in the cancer group were reported to have a normal taste function, which enabled them to perceive umami, one of the five basic taste compared to those in the control group. These findings demonstrated that gastric cancer patients experience post-surgical digestive issues, chemotherapy-induced changes in smell and taste, and appetite loss. To improve the quality of life of these patients and the efficacy of the treatment, it is necessary to consider not only their nutritional requirements but also other factors such as appetite loss and discomfort when developing meals specifically for them.

본 연구의 목적은 요가와 자매 학문으로서 삶의과학, 예방의학, 통합의학, 체질의학이라고 할 수 있는 아유르베다를 기반으로, 백세 시대의 건강을 목표로 미각을 중시하는 식생활교육 현장에서의 접 목법을 찾고자 했다. 연구방법으로는 아유르베다의 몸 이해를 위해 첫째, 독특한 개념인 3-도샤(바따, 피타, 카파)와 기능, 구조, 질료를 포함하는 개념인 7-다뚜(dhātu), 질료의 개념인 3-말라를 살펴보았 다. 둘째, 아유르베다의 6가지 맛(단맛, 신맛, 쓴맛, 짠맛, 매운맛, 떫은맛)의 의미와 현대 음식의 맛에 대해 문헌고찰. 셋째, 오감 중에 음식의 맛과 관련이 깊은 미각력을 중심으로 문헌고찰하였다. 또한, 미각교육 시 적용이 쉬운 간단 미각테스트 활용법과 함께 일상에서 현대인의 미각력을 높이는 특이 한 음식조합을 제시하였다. 결론에서는 아유르베다의 맛과 현대 음식의 맛 의미를 정리하면서 백세 시대를 사는 현대인들에게 아유르베다적 식생활법을 권장하고, 내 몸에 맞는 맛을 찾아가며 보다 건 강한 삶을 영위할 것을 제언했다.

This study investigates (1) the consumer characteristics of fresh-cut produce in Korea and (2) the expected taste of fresh-cut produce. To accomplish the first goal of this study, food purchase data from household panels collected by the Rural Development Administration from 2017 to 2020 were used. Further, an online survey was conducted about the expected taste regarding fresh-cut fruits and vegetables. The results revealed that younger consumers with more expenses on fresh fruits tend to buy more fresh-cut fruits. Similarly, younger consumers with more expenses on fresh vegetables and higher household incomes tend to purchase more fresh-cut vegetables. Furthermore, consumers expect more convenience from fresh-cut apples but less tastiness from fresh-cut apples than whole apples.

Taste is a basic sensation to get attracted toward nutritious foods or avoid possible harmful substances. The basic taste qualities in humans consist of sweet, bitter, umami, salty, and sour. Basically, sweet and umami tastes make food attractive, whereas bitter and sour tastes make it avoidable. Salty taste comprises basic salty and high salt taste. The basic salty taste is known as amiloride-sensitive salty taste, which is inhibited by amiloride, but the high salt taste is not sensitive to amiloride. Moreover, high salt taste can also cause avoidance behavior in human beings. Sodium, one of the most important cations in the body fluids of vertebrates, controls the volume of total body fluids and is a risk factor for cardiovascular diseases, such as hypertension. The concentration of sodium in body fluids must be under delicate control. A distinction between the salty taste and high salt taste would be a contributing mechanism to control the volume and/or osmolarity of body fluids.

Umami taste-yielding foods, such as, Joseonganjang, dried anchovies, dried shiitake, dried Konbu (kelp), and Yukjeot, are widely used in the Korean cuisine as soup base. While Umami taste enhancement related to Kokumi taste substances has been proposed in human sensory studies, the potential action of Kokumi taste substances has not been explored on calcium-sensing receptors (CaSR), here referred to as Kokumi taste receptors. In this study, we investigated the effect of Umami taste-yielding foods on Kokumi taste receptors using cells expressing human CaSR. We monitored the temporal changes in intracellular Ca2+ in HEK293T cells expressing CaSR in response to aqueous extract of Joseonganjang, dried anchovies, dried shiitake, dried Konbu, and Yukjeot. Kokumi substances tested-glutathione and γ-Glu-Val-Gly- evoked intracellular Ca2+ influx in a concentration-dependent manner. A similar increment of intracellular Ca2+ influx was induced by Joseonganjang, Yukjeot, and dried anchovies, but not by dried shiitake and dried Konbu. Only Joseonganjang- and Yukjeot-evoked intracellular Ca2+ influx was significantly reduced by NPS 2143, a CaSR-specific antagonist. These data indicated that some Umami substances/Umami-yielding materials could activate CaSR, but this property was not observed for all the Umami tasting substances.

청동기 이후 대리석이라는 매체의 (재)등장은 동방화라는 사회·문화상의 반영이자, 이후 고 대 그리스의 시각 문화를 전면적으로 바꾸는 중요한 사건이었다. 본 연구는 초기 철기 시대의 그 리스에서 대리석의 사용과 채굴, 수송 등에 관한 전반을 고찰하고, 초기 그리스 미술에서 대리석 을 향유한 개인과 그 작품들을 중심으로 기원전 7세기에 대리석이라는 새로운 매체가 지녔던 의 미를 추론하고자 한다. 기원전 7세기경 그리스 조각사에서 대리석은 그 향유자들에게 엘리트적 취향을 드러내기에 적합한 매체였다. 니칸드레와 에우티카르티데스, 그리고 <테라의 코레>의 주 인은 낙소스에서 나온 대리석이라는 새로운 매체를 선도적으로 활용함으로써 그들이 ‘선택된 자’, 즉 지역 사회의 엘리트라는 메시지를 전달하고자 하였다. 이들 초기 대형 독립상은 대리석이 라는 새로운 매체가 지역 사회 엘리트의 심미적 취향과 결합하는 그 시작점이었다.

본 연구는 전자 센서를 이용하여 다양한 추출방법에 따른 무 추출물들의 향미 특성을 조사하였다. 무의 신맛은 무 흰색 부위의 열수 추출물이 6.9의 센서 값을 나타내어 가장 높았다. 신맛은 8.0의 센서 값을 나타내어 무 초록색 부위의 콜드 브루 추출물이 가장 높았다. 감칠맛은 무 흰색 부위의 열수 추출물이 8.3의 센서 값을 나타내어 가장 높았다. 단맛은 무 초록색 부위의 콜드 브루 추출물이 6.8 의 센서 값으로 가장 높은 값을 나타내었고, 쓴맛은 무 초록색 부위의 고온 가압 추출물이 7.5의 센서 값으로 가장 높은 값을 나타내었다. 전자코를 이용하여 무 추출물들에서 총 16개의 휘발성 향기성분을 확인하였다. 무 추출물 속 휘발성 향기성분들 중 methanethiol이 주요한 향기성분으로 확인되었다. 본 연구에서 확인된 결과들은 무 추출 물의 향미 특성에 대한 기초 연구 자료로 활용될 수 있을 것으로 판단된다.

The salinity of the brining solution for preparing kimchi imparts saltiness to kimchi, and affects its overall taste. In this study, the changes in the overall taste and quality of kimchi depending on the salinity of the brining solution (6% and 12%) were investigated. The salinity of kimchi brined in 6% NaCl solution was approximately 1.3%, and its umami (2.22±0.22) was lower than that (2.96±0.16) of the conventional kimchi, brined in 12% NaCl solution. In contrast, its bitterness (-3.77±0.05) was higher than that of the conventional kimchi (-4.48±0.12). The sensory evaluation results showed that the overall taste score of the low-salinity kimchi (2.8±0.4) was significantly lower than that of the conventional kimchi (4.5±1.1). To overcome the deterioration in the overall taste, a taste enhancer with a sea tangle extract and anchovy extract was added to the low-salinity kimchi. The overall taste score (4.4±1.2) of the seasoned kimchi, which is the low-salinity kimchi supplemented with the taste enhancer, was comparable to that (4.5±1.1) of the conventional kimchi, while maintaining a salinity of 1.7%. This study demonstrated the benefits of proper taste enhancer for improving the taste of low-salinity kimchi.

본 논문에서는 취향공동체가 오늘날 가장 넓은 범위에서 사회의 구심적 역할을 할 수 있을 것이라 판단하고 이의 형성과 확산에 관해 분석하였다. 다양성과 다원성을 존중하며, 빠르게 진전되는 비대면 사회에 적응 하기 위해 취향공동체에 관해 진지하게 논의해 볼 필요가 있다. 이에 본 논문에서는 21세기 취향공동체가 사회 구심점 역할을 할 수 있을지에 주목하였다. 코로나로 인하여 비대면 시대가 앞당겨 다가온 현재, 취향이 기술과 결합하여 우리 사회 내 새롭게 공동체를 응집시키는 대안이 될 수 있다고 판단한다. 본고에서는 우선 취향공동체 및 트랜스미디어 스토리텔링에 관한 선행연구를 진행하였으며, BTS의 트랜스미디어 스토리텔링 활용과 팬문화로서의 취향공동체 확산에 관하여 분석하였다.

본 연구는 전자코와 전자혀 시스템을 이용한 15가지 국내 식품에 대한 맛과 향에 대한 기본 접근 연구를 진행하였다. 먼저 전자혀 시스템을 이용한 샘플의 맛 성분에 대해 상대적인 센서 강도를 제시하였다. 신맛으로 대표되는 SRS 센서에서는 소고기배추국이 가장 높은 9.0을 나타내었고, 미역국에서 가장 낮은 3.7을 나타내었다. 짠맛으로 대표되는 STS 센서는 오징어국에서 가장 높은 8.2를 나타내었고, 소고기배추국이 가장 낮은 1.9를 나타내었다. 감칠맛으로 확인되는 UMS 센서의 경우 소고기배추국이 가 장 높은 10.1을 보였고, 달걀국이 가장 낮은 3.3을 나타내었다. 단맛에 관여하는 SWS 센서에서는 비교적 큰차이를 보이지 않았는데, 시금치된장국이 가장 높은 7.3을 나타내 었고, 달걀국이 가장 낮은 4.6을 나타내었다. 마지막으로 쓴맛에 기여하는 BRS 센서에서는 시래기 된장국이 가장 높은 7.8을 나타내었으며, 햄김치찌개에서 가장 낮은 4.4를 보였다. 주성분 분석을 통해 5가지 맛 성분과 15가지 샘플에 대한 패턴을 확인한 결과 PC1에서 56.21%의 variance를 확인하였고, PC2에서 25.23%의 variance를 확 인할 수 있었다. 각 맛 성분의 경우 SRS 센서의 경우 PC1 과 PC2의 factor loading의 경우 -0.95와 -0.20을 나타내었고, STS 센서의 경우 PC1과 PC2의 factor loading의 값이 0.96과 0.14, UMS 센서의 경우 PC1과 PC2의 factor loading의 값이 -0.94와 0.22, SWS 센서의 경우 PC1과 PC2 의 factor loading의 값이 0.08과, 0.89, 그리고 BRS 센서의 경우 PC1과 PC2의 factor loading의 값이 0.32와 -0.60을 각각 나타내었다. 군집분석을 통해 확인된 샘플간의 유사도 는 크게 4개의 cluster를 확인할 수 있었다. 15가지 샘플에 서 확인된 향기성분은 총 25가지 성분이 확인되었고, 모든 샘플에서 상대적으로 가장 높은 함량을 보이는 향기성분 은 ethanol과 2-methylthiophene으로 확인되었다. 주성분 분석을 통해 휘발성 향기 성분과 15가지 샘플에 대한 패턴을 확인한 결과 PC1에서 28.54%의 variance를 확인하였고, PC2에서 20.80%의 variance를 확인할 수 있었다. 군집분석의 경우 크게 3개의 cluster로 분류되는 것을 확인 할 수 있었다. 이러한 맛과 향에 대한 연구를 통해서 국내 식품에 대한 표준 자료로써의 활용이 가능할 것으로 판단된다.

The preparation of commercial, low-salinity kimchi needs to be carefully monitored to maintain the taste of kimchi. To address this, the taste profiles of three brands of commercial kimchi were examined using a taste sensing system, as well as a sensory evaluation. The average sensory score (4.3/9.0) in the overall taste of low-salinity kimchi (A', B', and C') was significantly lower than that (5.1/9.0) of conventional kimchi (A, B, and C). The explanation for the result of A' seemed to be its decrease in saltiness (3.51) and increase in bitterness (8.55) compared to those (6.55 and 7.65, respectively) of A. In B', the saltiness (4.25) and the overall taste (3.7) were significantly decreased compared to B (6.23 and 4.8, respectively). Interestingly, no significant difference was observed in the overall taste (5.1) and saltiness (6.70) of C' when compared to C (5.3 and 6.46, respectively), confirming that salinity is a crucial factor in determining overall taste. Consistent with this finding, the overall taste of low-salinity kimchi correlated positively with its saltiness (>0.98) and umami (>0.82). These results advocate the careful determination of salinity required to maintain the taste of conventional kimchi in preparing low-salinity kimchi, while also pointing towards the need to develop effective taste enhancers for supplementing overall taste.

The purpose of this study was to confirm changes in flavor and taste characteristics of black pepper by combining nonthermal sterilization treatment methods, namely intense pulsed light, cold plasma, and ultraviolet. After treatment, lightness value and hue angle of black pepper were decreased. The difference in chromaticity between samples before and after treatment showed a significant difference of 6.11. The piperine contents before and after the combined nonthermal sterilization treatment were reduced from 28.4±0.25 mg/g to 20.4±1.06 mg/g. The results of an intensity test showed that the color and flavor of the sample became darker and weaker, but hot and pungent were not distinguished after nonthermal treatment. The flavor profile showed that the intensity of cool flavor was decreased, the intensity of nutty taste was increased, and other sensory languages did not show any difference. Although differences in flavor and taste were distinguished in a cooking application, the differences were not significant.