목적 : 본 연구는 라쉬 분석을 통해 장애 아동 부모의 한국판 의미있는 활동 참여 척도(Korea-Engagement Meaningful Activity Survey; K-EMAS)의 타당성을 검증하여 장애아동 부모의 활동에 대한 주관적 가치와 의미를 체계적으로 평가하고 측정할 수 있는 기초자료로 제시하고자 한다. 연구방법 : 장애 아동을 양육하는 부모 84명을 대상으로 K-EMAS 평가를 시행하였다. 이후, 라쉬 분석을 통하여 대상자 와 항목의 적합도, 평정척도, 항목 난이도, 분리 신뢰도를 분석하였다. 결과 : 84명의 대상자 중 설문이 끝까지 이루어지지 않거나 표기한 내용이 정확하지 않은 설문을 제외한 80부를 분석에 사용하였다. 분석에서 부적합 대상자로 나타난 9명의 결과를 제외하였으며, 이후 71부의 결과를 통해 항목 적합도의 분 석을 실시하여 12개 항목이 적합한 항목으로 나타났다. 또한, 항목 난이도 분석에서는 ‘창의성’ 항목이 가장 높은 난이도 로, ‘자신 돌보기’가 가장 낮은 난이도 항목으로 나타났다. 평정척도 분석 결과 5점 척도가 적합한 것으로 나타났으며, 대 상자 분리지수 4.98, 분리 신뢰도 0.96, 항목 분리 지수 2.02, 분리 신뢰도 0.80 으로 나타났다. 결론 : 본 연구는 장애 아동 부모를 대상으로 활동 참여를 객관적으로 판단할 수 있는 평가도구의 타당성을 검증하였다. 본 연구결과를 바탕으로 후속 연구에서는 문항 난이도를 조절하여 수정된 평가도구로 전국지역의 다양한 연령, 진단군의 아동의 부모를 대상으로 한 연구가 추후 이루어져야 할 것으로 보인다.

Antioxidants are food additives that extend the shelf life of food products by preventing lipid rancidity caused by active oxygen. They can either be naturally-derived or manufactured synthetically via chemical synthesis. In this study, method validation of five synthetic antioxidants, namely butylated hydroxyanisole, butylated hydroxytoluene, tertiary butylhydroquinone, propyl gallate, and disodium ethylenediaminetetraacetic acid, was performed using a high performance liquid chromatography–ultraviolet visible detector, and the method applicability was evaluated by analyzing foods containing antioxidants. The coefficient of determination (R2) average was 0.9997, while the limit of detection and limit of quantification were 0.02–0.53 and 0.07–1.61 mg/kg, respectively. The intra and inter-day accuracies and precisions were 83.2±0.7%–98.7±2.1% and 0.1%–5.7% RSD, respectively. Inter-laboratory validation for accuracy and precision was conducted using the Food Analysis Performance Assessment Scheme quality control material. The results satisfied the guidelines presented by the AOAC International. In addition, the expanded uncertainty was less than 16%, as recommended by CODEX. Consequently, to enhance public health safety, the results of this study can be used as basis data for evaluating the intake of synthetic antioxidants and assessing their risks in Korea.

해수면온도는 해양-대기의 현상을 이해하고 기후변화를 예측하기 위해 사용되는 중요한 변수이다. 마이크로파 영역의 인공위성 원격탐사는 구름과 강수와 같은 기상현상 위성 관측 측기의 경로에 존재하더라도 해수면온도 획득을 가능하게 한다. 따라서 마이크로파 해수면온도의 높은 활용도를 고려하면 위성 해수면온도를 정확도를 지속적으로 검증 하고 오차 특성을 분석할 필요가 있다. 본 연구에서는 2014년 3월부터 2021년 12월까지 약 8년 동안 Global Precipitation Measurement (GPM)/GPM Microwave Imager (GMI) 마이크로파 해수면온도의 정확도를 표층 뜰개 부이 수온 자료를 사용하여 검증하였다. GMI 해수면온도는 실측 해수면온도에 비해 0.09 K의 편차와 0.97 K의 평균 제곱근 오차를 보였 고, 이는 기존 연구 결과에 비해 다소 높게 나타났다. 이외에도 GMI 해수면 온도의 오차 특성은 위도, 연안과의 거리, 해상풍 및 수증기량과 같은 환경적 요인과 관련성이 있다. 오차는 육지에서 300 km 이내의 거리에서 해안 지역에 가까 운 지역과 고위도 지역에서 증가하는 경향이 있다. 또한 낮에는 약한 풍속(<6 m s−1 ), 밤에는 강한 풍속(>10 m s−1 ) 범위 에서 상대적으로 높은 오차가 나타났다. 대기 수증기는 30 mm 미만의 매우 낮은 범위 또는 60 mm보다 큰 매우 높은 범위에서 높은 해수면온도 차이에 기여했다. 이러한 오차들은 저수온에서 GMI 자료의 정확도가 떨어지는 기존 연구와 일치하며, 연안으로부터의 거리, 풍속, 수증기량에 의한 오차의 경우 육지와 해양의 방사율 차이 및 바람에 의한 해수 면 거칠기 변화, 수증기의 마이크로파 대기 흡수에서 기인하는 것으로 추정된다. 이는 한반도 주변해에서 마이크로파 위성 계산 SST를 보다 광범위하게 활용하기 위해서는 GMI 해수면온도 오차의 특성에 대한 이해가 필요함을 시사한다.

본 연구는 기업의 중간관리자, 코칭역량 척도(CCSMM)의 신뢰도와 타당도를 검증하는데 목적이 있다. 타당화 연구를 위한 중간관리자의 코칭역량 척도의 문항 구성요인은 목표달 성, 커뮤니케이션, 대인관계, 자기주도의 4개 영역과 목표정하기, 목표달성, 경 청, 질문, 피드백, 상호존중 및 신뢰, 지지 및 지원, 자기효능감 및 성장/미래지향 성의 9개 요인 40문항으로 구성되어 있다. 상기와 같이 새롭게 개발된 중간관리자의 코칭역량 척도의 일반화를 위해 타 당도의 증거를 제시하고자, 기존의 타당화된 검사 도구와의 상관계수를 확인하 였다. 상관관계 분석결과 중간관리자의 코칭역량 척도와 Stowell(1986)의 코칭 리더십 척도 간에 높은 유의미한 정적상관을 보였다. 즉, 목표정하기, 목표달성, 경청, 질문, 피드백, 상호존중 및 신뢰, 지지 및 지원, 자기효능감, 성장/미래지향 성 등 중간관리자의 코칭역량 구성요인과 코칭리더십 척도 간에 모두 유의미한 정적상관이 있다는 것이 밝혀졌다. 결론적으로 본 연구는 기업의 중간관리자, 코칭역량 척도의 신뢰도와 타당도 의 타당화 검증을 통해 기업에 근무하는 중간관리자들의 코칭역량 향상에 기여 할 수 있는 계기가 되었다는 데 의의가 있다.

We established pretreatment method of solidified cement ion-exchange resin samples generated before 2003 in nuclear power plants for measurement of non-volatile radionuclide activity. A microwave digestion system (MDS) with mixed acid (HCl-HNO3-HF-H2O2) was used to dissolve cement and to desorb non-volatile elements such as Ce, Co, Cs, Fe, Nb, Ni, Re, Sr and U from mixed ion-exchange resin. The content of Ce, Co, Fe, Nb, Ni, Re, Sr, U and Cs after pretreatment of cement plus mixed ion-exchange resin was measured by ICP-AES and ICP-MS, respectively. As iron and strontium are also present in cement, their content after dissolving a certain amount of cement was measured by ICP-AES. All elements except Nb were quantitatively recovered. Especially since the Nb recovery was low at 72.0±2.5%, the MDS following addition of the mixed acid to the resin was operated once more for desorbing Nb from it. Finally the recovery of Nb was over 95%. This sample pretreatment method will be applied to solidified cement ion-exchange resin samples generated in nuclear power plants for assessment of radionuclide inventory.

Combustion method has been widely used in the analysis of 3H and 14C in various types of radioactive wastes since X. Hou reported the analysis of 3H and 14C in graphite and concrete for decommissioning of nuclear reactor. In this work, it was demonstrated that the validation result of combustion method for the simultaneous analysis of 3H and 14C in non-combustible radioactive wastes. To validate the combustion method, 3H and 14C spiked to sea sand and soil were prepared and each simulated sample was combusted with the accordance to a combustion temperature program. The validation of combustion method was assessed by the radioactivity recovery, radioactivity deviation, and relative standard deviation of measured radioactivity. The results of radioactivity recovery, radioactivity deviation, and relative standard deviation of 14C were 100~105%, less than 7%, less than 5%, respectively. In addition, 3H showed about 90% of radioactivity recovery, less than 20% of radioactivity deviation, and less than 5% of relative standard deviation. It will be provided that the validation results of combustion method in detail.

As the zircaloy cladding absorbs an excessive amount of hydrogen and cooled down under hoop stress, radial hydride may be precipitated by hydride reorientation phenomenon. There have been many previous studies about the threshold stress of the reorientation, but it is known that the quantitative degree of hydride reorientation rather than the threshold is important for the prediction of mechanical properties. A thermodynamic model for Radial Hydride Fraction (RHF) prediction has been developed in this study. The model calculates RHF with respect to temperature, cooling rate, hydrogen content, and applied stresses. Once the cooling rate is given, the solid solution concentration at each temperature is determined by Hydrogen-Nucleation-Growth-Dissolution model. Subsequently, the increment of radial hydride is derived by nucleation and growth theory. The code based on the thermodynamic theory can provide the prediction of RHF under hoop stress, as well as a change in precipitation behavior over time. RHF of the zircaloy cladding in long-term dry storage can be obtained by the implementation of the code and the degradation of the cladding is directly estimated according to the correlation between RHF and mechanical properties. Ongoing experimental validation of the developed model is discussed.

To ensure the peaceful use of nuclear energy, nuclear safeguards are applied in member states of the International Atomic Energy Agency (IAEA) under the Non-Proliferation Treaty. The two major considerations in implementing nuclear safeguards are effectiveness and efficiency. In terms of efficiency, the IAEA has a great interest in using containment and surveillance (C/S) technology to maintain continuity of knowledge. A representative means of C/S technology is a sealing system to detect tampering. The existing sealing systems used by the IAEA are of limited functionality in realtime verification purposes. To address this limitation, the present study develops a real-time verification sealing system. First, we analyzed the design requirements of a sealing system proposed by various institutions including the IAEA, the U.S. Nuclear Regulatory Commission, and a number of national laboratories and companies. Then, we identified the appropriate design requirements of this system for real-time verification. Finally, the prototype system was developed and tested based on the identified design requirements. The validation tests of the prototype system were performed for anticipated environmental conditions, radiation resistance, and safeguards functionality. Additionally, we are developing user-friendly verification software. The software validation is planned to perform for functionality, performance efficiency, and security. The next step is to develop a commercialized realtime verification sealing system based on the results of validation tests. Using this commercialized system, we plan to evaluate the performance in various actual use cases. Such a system is expected to significantly enhance the efficiency of nuclear safeguards.

본 연구는 발효노니 다당체 추출물(Vitalbos)을 건강기능 식품 소재로 활용하기 위해 DAA, 총당 함량, 단당류 3종 (galacturonic acid, glucose 및 galactose)을 지표성분으로 설정하고, 지표성분에 대한 효과적인 분석법 설정 및 검 증을 위해 수행되었다. 기존에 보고된 분석법 검증 방법 을 수정하여 특이성, 직선성, 정밀성, 정확성, 검출한계 (LOD) 및 정량한계(LOQ)를 고성능 액체크로마토그래피와 페놀-황산법을 이용하여 측정하였다. 그 결과 DAA 및 단 당류 3종의 표준용액과 Vitalbos의 머무름 시간이 일치하 였으며 스펙트럼 또한 동일하여 분석법의 특이성을 확인 하였다. 지표성분의 검량선 상관계수(R2)는 0.9995-0.9998 범위로 0.99 이상의 우수한 직선성을 나타냈다. Intra-day 및 inter-day 정밀도는 0.14-3.01%의 범위로 5% 미만의 우 수한 정밀도를 나타냈고 회수율은 95.13-105.59% 범위에 서 우수한 정확도를 보였다. DAA 분석의 LOD와 LOQ는 각각 0.39 μg/mL 및 1.18 μg/mL이었으며 총당 함량의 LOD 및 LOQ는 각각 0.84 μg/mL 및 2.55 μg/mL로 측정 되었다. 단당류 3종에 대한 LOD는 0.48-0.81 μg/mL의 범 위였으며, LOQ는 1.45-2.44 μg/mL 범위에서 정량분석이 가능한 것으로 나타났다. 분석법 검증 결과, 특이성, 직선 성, 정밀성 및 정확성 모두 우수한 분석법임을 검증하였 으며, LOD와 LOQ 또한 Vitalbos 분석에 적합하였음을 확 인하였다. 검증된 분석법을 이용하여 Vitalbos의 지표 성분 함량을 측정하였을 때, DAA, 총당 함량, galacturonic acid, glucose 및 galactose의 함량은 각각 2.31±0.06 mg/dry weight g, 475.92±5.95 mg/dry weight g, 72.83±1.05 mg/dry weight g, 71.63±2.44 mg/dry weight g 및 67.30±2.31 mg/dry weight g으로 측정되었다. 본 연구에서 검증된 분석법을 사용했을 때 Vitalbos의 지표성분 3종에 대하여 우수한 재현성으로 정 량분석이 가능하였으며, 건강기능식품 소재로의 품질관리에 기여할 수 있을 것으로 판단된다.

본 연구에서는 3D 프린팅 FDM 방식의 적층 방향에 따라 기계적 물성이 달라지는 이방성 특성을 확인하고 이를 이용하여 위상 최 적설계를 수행하였다. 벤치마크 문제인 자동차 현가장치 부품 중 하나인 로어 컨트롤 암에 대하여 밀도법 기반 위상 최적설계를 수행 하였으며, 외부 하중과 이방성 특성에 따라 위상 최적결과가 다르게 나타나는 것을 확인하였다. 이를 이용하여 최적화된 모델에 대하 여 3D 프린터로 적층 방향을 달리하여 2가지 시험품을 제작하였으며 인장시험을 수행하였다. 시험시 3D 비접촉 변형률 측정기를 이 용하여 변형률을 구하였으며 이를 CAE 응답해석으로 얻은 변형률과 비교한 결과가 정량 및 정성적으로 일치하는 것을 확인하였다. 3D 프린팅 적층 방향을 고려한 위상 최적모델의 인장 실험 결과를 통해 해당 최적설계 방법론의 유효성을 검증하였다.

This study was to investigate an analytical method for determining dieckol content in Ecklonia stolonifera extract. According to the guidelines of International Conference on Harmonization. Method validation was performed by measuring the specificity, linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) of dieckol using high-performance liquid chromatography–photodiode array. The results showed that the correlation coefficient of calibration curve (R2) for dieckol was 0.9997. The LOD and LOQ for dieckol were 0.18 and 0.56 μg/mL, respectively. The intra- and inter-day precision values of dieckol were approximately 1.58-4.39% and 1.37-4.64%, respectively. Moreover, intra- and inter-day accuracies of dieckol were approximately 96.91- 102.33% and 98.41-105.71%, respectively. Thus, we successfully validated the analytical method for estimating dieckol content in E. stolonifera extract.

This study installed and evaluated the efficiency of a radon barrier membrane, radon mat, and radon well in the removal and reduction of radon gas that originates from the soil and flows indoors. The study aims to present a fundamental and long-term solution to radon reduction in buildings by preventing soil radon, which is the main source of radon gas, from migrating indoors. A radon barrier membrane, radon mat, and radon well were developed and verified, and the radon reduction effect of each system was evaluated. Through applying a special radon gas blocking film with a 5-layer structure, the radon barrier membrane prevents radon gas particles from passing through the polymer deposited on the radon blocking film. The radon mat is a type of radon reduction construction method that induces radon gas generated from the soil under the building to move in the desired direction through the plate-structured pressure reducing panel and discharges radon gas to the outside of the building through an exhaust pipe and fan installed at the edge. In addition, the radon well can also be applied to special structures such as old buildings and historical sites where it is difficult to directly reduce radon concentration within the building foundation, because the intake area can be controlled and, therefore, the method can be applied in a variety of environments and ranges. In the case of Intervention 1 (installing a radon barrier membrane and radon mat), the soil radon was reduced by 24.7%. Intervention 2 (installing a radon barrier membrane, radon mat, and radon well) reduced the soil radon by 45.1%, indicating that the effect of reducing the soil radon concentration was 1.8 times higher compared with installing only the radon barrier membrane and radon mat. The measurement showed that the indoor radon concentration was reduced by 46.5%, following the reduction in soil radon concentration through Interventions 1 and 2, demonstrating the effect of reducing indoor radon gas by installing the radon barrier membrane, radon mat, and radon well. Through the production and installation of prototype systems, this study confirmed the reduction effect of radon concentration in soil and indoor air. These systems achieved a higher efficiency at a relatively low cost than that achieved with the existing radon reduction methods applied in Korea and abroad.

Non-destructive estimation of leaf area is a more efficient and convenient method than leaf excision. Thus, several models predicting leaf area have been developed for various horticultural crops. However, there are limited studies on estimating the leaf area of strawberry plants. In this study, we predicted the leaf areas via nonlinear regression analysis using the leaf lengths and widths of three-compound leaves in five domestic strawberry cultivars (‘Arihyang’, ‘Jukhyang’, ‘Keumsil’, ‘Maehyang’, and ‘Seollhyang’). The coefficient of determination (R2) between the actual and estimated leaf areas varied from 0.923 to 0.973. The R2 value varied for each cultivar; thus, leaf area estimation models must be developed for each cultivar. The leaf areas of the three cultivars ‘Jukhyang’, ‘Seolhyang’, and ‘Maehyang’ could be non-destructively predicted using the model developed in this study, as they had R2 values over 0.96. The cultivars ‘Arihyang’ and ‘Geumsil’ had slightly low R2 values, 0.938 and 0.923, respectively. The leaf area estimation model for each cultivar was coded in Python and is provided in this manuscript. The estimation models developed in this study could be used extensively in other strawberry-related studies.

This study aimed to investigate the validation and modify the analytical method to determine quercetin- 3-o-gentiobioside and isoquercitrin in Abelmoschus esculentus L. Moench for the standardization of ingredients in development of functional health products. The analytical method was validated based on the ICH (International Conference for Harmonization) guidelines to verify the reliability and validity there of on the specificity, linearity, accuracy, precision, detection limit and quantification limit. For the HPLC analysis method, the peak retention time of the index component of the standard solution and the peak retention time of the index component of A. esculentus L. Moench powder sample were consistent with the spectra thereof, confirming the specificity. The calibration curves of quercetin-3-o-gentiobioside and isoquercitrin showed a linearity with a near-one correlation coefficient (0.9999 and 0.9999), indicating the high suitability thereof for the analysis. A. esculentus L. Moench powder sample of a known concentration were prepared with low, medium, and high concentrations of standard substances and were calculated for the precision and accuracy. The precision of quercetin-3-o-gentiobioside and isoquercitrin was confirmed for intraday and daily. As a result, the intra-day precision was found to be 0.50-1.48% and 0.77-2.87%, and the daily precision to be 0.07-3.37% and 0.58-1.37%, implying an excellent precision at level below 5%. As a result of accuracy measurement, the intra-day accuracy of quercetin-3-o-gentiobioside and isoquercitrin was found to be 104.87-109.64% and the daily accuracy thereof was found to be 106.85-109.06%, reflecting high level of accuracy. The detection limits of quercetin-3-o-gentiobioside and isoquercitrin were 0.24 μg/mL and 0.16 μg/mL, respectively, whereas the quantitation limits were 0.71 μg/mL and 0.49 μg/mL, confirming that detection was valid at the low concentrations as well. From the analysis, the established analytical method was proven to be excellent with high level of results from the verification on the specificity, linearity, precision, accuracy, detection limit and quantitation limit thereof. In addition, as a result of analyzing the content of A. esculentus L. Moench powder samples using a validated analytical method, quercetin-3-o-gentiobioside was analyzed to contain 1.49±0.01 mg/dry weight g, while isoquercitrin contained 1.39±0.01 mg/dry weight g. The study was conducted to verify that the simultaneous analysis on quercetin-3-o-gentiobioside and isoquercitrin, the indicators of A. esculentus L. Moench, is a scientifically reliable and suitable analytical method.

본 논문은 범용성 기기를 기반으로한 가속도계로 라즈베리파이 4B 기반 MEMS형 가속도계 ADXL345와 iPhone 12 pro 내 장형 가속도계를 사용하여 다자유도 축소 모형 구조물의 응답을 계측하고 그 결과를 IEPE타입 가속도계와 비교하여 계측 유효성을 확 인하고자 하였다. 1~3층 모형 구조물 최상층에 충격해머로 가진하였으며 각 층의 가속도를 측정하였다. 시간영역에서 모든 가속도계 의 계측값이 대체적으로 유사한 결과를 나타냈으며 진동수영역에서 모드진동수 또한 유사하게 나타났다. 감쇠비와 모드형상 추정에 있어서 라즈베리파이 기반 ADXL345보다 iPhone 12 pro가 더 정확한 결과를 보였으나 대체적으로 유사하게 나타났다. 실험 결과를 바 탕으로 라즈베리파이 기반 ADXL345와 iPhone 12 pro 가속도계의 구조물 식별 유효성을 확인하였다.

The objective of this study was to develop a simultaneous method for 8 amino acids including alanine, arginine, glutathione, lysine, ornithine, methionine, threonine and tryptophan in veterinary products using LC-MS/MS. To optimize MS analytical condition of 8 amino acids, each parameter was established by multiple reaction monitoring in positive mode. The chromatogram separation was achieved on a C18 column with mobile phase of 0.1% formic acid in D.W. and 0.1% formic acid in acetonitrile for green technology at a flow rate of 0.4mL/min for 5 min with gradient elution. The developed method was validated for mass accuracy, precision, linearity in veterinary products. Calibration curves were linear over the calibration ranges (0.5 – 10 mg/L) for all the analytes r2>0.99. Average recoveries were 92.96 – 105.61% and relative standard deviations (RSD) were 0.27 – 3.5%. The limit of detection (LOD) and the limit of quantification (LOQ) were 0.04 – 0.83 mg/L and 0.12 – 2.52 mg/L, respectively. All values were corresponded with the criteria ranges requested by CD 2002/657/EC. The application of this method will be helpful in quality control analysis of amino acids in veterinary products.