This study investigated the anti-obesity effects of Coriandrum sativum L. ethanol extracts in a high fat diet-induced obesity model (DIO). We confirmed the anti-obesity effects by analysing the expression of the related proteins, weight gain, dietary intake, dietary efficiency, blood biochemistry, histological analysis and western blot analysis. After oral administration of Coriandrum sativum L. ethanol extracts at concentrations of 250 and 500 mg/kg, a significant improvement in dietary efficiency, reduction in weight gain, triglycerides, total cholesterol and LDL-cholesterol in blood lipid was observed for 8 weeks. In addition, improvement in blood glucose and metabolism confirmed through glucose tolerance test was observed. Further, the concentration of alanine transaminase (ALT) in blood was significantly decreased, which improved the fatty liver caused by high-fat diet intake as confirmed by liver tissue analysis. This phenomenon was confirmed to decrease the expression of fat accumulation-related PPARγ and FAS protein in the liver tissue. Especially, it is believed that FAS, a liposynthetic enzyme, has a stronger inhibitory effect than PPARγ. Therefore, Coriandrum sativum L. ethanol extract is thought to improve obesity by reducing blood lipids levels, improving glucose metabolism and inhibiting synthesis of the fat that accumulates in the liver in high-fat diet-induced obesity animal models.

본 연구는 국내의 호스피스 제도와 불교인을 위한 호스피스 프로그램의 현실을 살펴보고, 불교인 말기 환자를 위한 호스피스 프로그램을 만들기 위해 필요한 불 교적 호스피스의 개념적 모델을 도출하는 데에 목적을 두고 있다. 실제로 국내의 불교계는 한국불교 호스피스협회가 불교 이념에 바탕을 둔 실천 활동을 전개하였 으나 보급과 실천에 한계를 보였고, 최근에는 국내의 호스피스 분야는 병원의 의 료현장 위주의 호스피스가 주류를 이루고 있다. 이와 같은 현실에서 불교 호스피 스 전문가의 양성을 모색하는 것보다는 국내의 호스피스 병원에서 간호사가 직접 쓰기에 적합한 ‘불교인을 위한 호스피스 프로그램’을 만들어 보급하는 것이 더 실 용적이라고 본다. 국내 의료현장에 불교인에 적합한 호스피스 서비스가 보급되기 위해서는 병원의 간호사와 호스피스 봉사자들이 배워서 현장에서 활용할 수 있는 불교적 호스피스 서비스 모델이 개발·보급되어야 한다. 이와 같은 취지로 본 연구 는 간호학의 ‘평화로운 생의 임종 이론’을 기반으로 불교적 관점에 적합한 불교적 호스피스의 개념 모델을 도출하였다. 이러한 불교적 호스피스 모델을 기존의 병원 에 보급하여 간호사 및 호스피스 교육에 사용된다면 불교 호스피스 활성화를 기 대해 볼 수 있다.

한국 혁신 생태계는 후발 추격자에서 ‘민간 주도의 건강하고 역동적인 생태계 조성을 위한 정부의 역할이 중요한’ 창조적 선도자 단계로 진화해 왔다. 한국의 혁신 생태계는 그동안의 획기적인 발전과 양적 확대에도 불구하고 혁신 성과의 정체 현상, 생태계 내 및 글로벌 연계 활동의 부족 등을 보여주고 있다. 미래 지향적인 혁신 생태계 조성을 위한 차세대 혁신 생태계 모델이 요구되는 상황이다. 기존의 이론적 근거를 바탕으로 혁신 생태계의 바탕을 이루는 것이 기업간 네트워크라는 관점에서 차세대 혁신 생태계의 요소로 기업간 네트워크 외에, 기업 역량, 공공 연구기관, 민간 산업단체, 기술 인프라, 정책 주체를 바탕으로 5개 요소를 설정하고, 불연속적 기술 및 시장 변화에 부응하는 ‘민간 주도의 건강하고 역동적인’ 혁신 생태계로서의 차세대 혁신 생태계 모델을 제시하였고 혁신 생태계구축 역할을 담당하는 정책 주체의 구체적인 방향을 제시하고, 본 연구의 의의를 제시하였다.

본 연구는 제15차(2019) 청소년건강행태조사의 원시자료를 활용하여 생물-심리-사회 모델을 바탕으로 우리나라 청소년의 편의식품 섭취 경험의 영향요인을 파악하고자 하였다. 연구 결과 생물학적 요 인으로 성별, 학년, 아토피 피부염이 주요 요인으로 분석되었으며, 심리학적 요인으로는 스트레스 인지 수 준, 우울감 경험, 자살 생각 여부, 주관적 수면충족, 주관적 건강상태, 신체활동, 현재 흡연과 음주 경험이 영향요인으로 확인되었다. 또한 사회학적 요인으로는 영양 및 식이 교육, 아침식사 여부, 학업 성적, 주관 적 경제상태, 동거가족 여부가 청소년의 편의식품 섭취 경험에 영향을 미치는 것으로 나타났다. 이러한 결 과를 바탕으로 청소년의 건강한 식습관 관리를 위해서는 실효성 있는 영양 및 식이교육 프로그램 제공과 정서적 지지가 필요하며, 가족 구성원을 교육 대상에 포함시키는 등 다각적이고 체계적인 대책마련이 필요 하다.

우리나라 열병합 발전소에서 운영되고 있는 최신 증기터빈의 출력과 효율 향상을 위한 첫 번째 기술적인 진보는 고온, 고압의 증기를 사용할 수 있는 소재 개발의 진척이라고 할 수 있다. 소재의 발전과 더불어 증기터빈의 내부효율 향상을 위한 설계적 노력의 결실 로 높은 효율의 증기터빈이 제작되었다. 오랜 기간 운전 중인 증기터빈의 내부효율은 기계적 수명의 한계로 점차 손실이 발생하고 효율 과 출력이 떨어지게 된다. 이러한 이유로 본 연구에서는 상용프로그램을 이용하여 열병합 발전소용 고압(HP)-중압(IP) 증기터빈의 증기유 로 성능해석을 수행할 수 있는 모델을 개발하고 성능계산 방법을 제시하고자 한다. 증기터빈의 복잡한 성능계산방식으로 인해 증기터빈 실무자들에게 실질적으로 유용한 참고문헌이 될 수 있도록 주요 변수들을 제시하였다. 또한 증기터빈 성능계산에 필요한 열정산도 분석 과 증기터빈 성능계산 결과의 적합성을 성능시험 결과와 비교 확인하였다.

The cutting process, which is a key processing technology in various industrial fields is achieving continuous growth, and the demand for high-quality cutting surfaces is continuously demanded. Plasma cutting continues to be studied for its excellent workability and productivity, but problems with cutting surface quality such as dross formation occur, so research to secure excellent cutting surface quality through appropriate control of process variables is essential. In this study, we propose a method for predicting surface roughness using real-time current and cutting speed data obtained while performing plasma cutting on A106 B steel pipe. Surface roughness was predicted based on the RBF algorithm applicable to prediction and control models. It was shown that the surface roughness of the plasma cutting surface can be predicted with the arc current waveform and process speed data. This study can be used as a basic study to control the surface roughness of the cut surface in real time.

Aluminum alloy-based additive manufacturing (AM) has emerged as a popular manufacturing process for the fabrication of complex parts in the automotive and aerospace industries. The addition of an inoculant to aluminum alloy powder has been demonstrated to effectively reduce cracking by promoting the formation of equiaxed grains. However, the optimization of the AM process parameters remains challenging owing to their variability. In this study, the response surface methodology (RSM) was used to predict the crack density of AM-processed Al alloy samples. RSM was performed by setting the process parameters and equiaxed grain ratio, which influence crack propagation, as independent variables and designating crack density as a response variable. The RSM-based quadratic polynomial models for crack-density prediction were found to be highly accurate. The relationship among the process parameters, crack density, and equiaxed grain fraction was also investigated using RSM. The findings of this study highlight the efficacy of RSM as a reliable approach for optimizing the properties of AM-processed parts with limited experimental data. These results can contribute to the development of robust AM processing strategies for the fabrication of highquality Al alloy components for various applications.

본 논문에서는 인장 좌굴 현상을 소개하고 이를 이용한 음의 포아송 효과를 가지는 구조물에 대한 분석을 다룬다. 일반적으로 널리 알려진 좌굴은 압축하중 하에서의 안정성 문제임에 반하여, 인장 좌굴은 인장에 의해 국소적으로 압축력이 생겨 발생하는 좌굴이다. 고전적인 좌굴에 비하여 비교적 최근의 연구이기 때문에 상대적으로 잘 알려지지 않았다. 이에 인장 좌굴 현상을 에너지 관점에서 고 찰하고, 해석을 위하여 비틀림 스프링을 가지는 비선형 트러스 유한요소의 정식화를 수행하였다. 비선형해석을 통해 후좌굴 거동을 분석하고 비틀림 스프링이 주요 인자임을 확인하였다. 이러한 후좌굴 거동은 음의 포아송 비를 가지는 구조물에 적용할 수 있으며, 기 계적 스위치 등의 장치에 적용할 가능성을 보였다. 얻어진 결과들의 정확성 확인을 위하여 해석해와 상용 유한요소해석 결과들과 비 교하여, 개발된 유한요소 모델이 기초 설계에 유용함을 보였다.

The objective of this study was to determine the efficacy of a natural product of cherry tree (Prunus serrulata var. spontanea: PS) as a test substance for improving cytokine and ovalbumin-specific IgE using an ovalbumin-induced asthma disease model of 5-week-old male BALB/c mice. Lung tissue pathology was analyzed to confirm anti-inflammatory and asthmatic effects. As a result of examining the effect on changes in inflammatory cells in bronchoalveolar lavage fluid in an ovalbumin-induced asthma disease model by administering the PS sample, total cells, eosinophil, neutrophil, lymphocyte, and monocytes were significantly decreased. Concentrations of cytokine-based TNF-alpha and IL-4 and immunoglobulin E in serum were significantly increased in the asthma-inducing negative control group than in the normal group. However, high concentrations of PS decreased them. In histopathological examination of the lung tissue, it was confirmed that inflammatory cells infiltrated around the alveoli and bronchioles were increased in ovalbumin-induced asthma disease model. After administration of cherry tree extract, bronchiolar morphological changes such as mucosal thickening were slightly improved. From the above results, it was confirmed that extract of cherry tree significantly reduced inflammation expression and tissue damage in alveolar tissues. It was also confirmed that the cherry tree extract had an excellent efficacy in improving asthma inflammation.

정서표상에 대한 논의 중 첫 번째는 정서가 차원에서의 정서표상, 두 번째는 감각양상에 따른 정서표상을 설명하는 것이 다. 선행연구에서는 정서표상을 설명하기 위해 정서가 모델(부호 정서가, 비부호 정서가), 감각양상에 따른 정서표상 모델 (감각보편성, 감각특징성)들이 제시되었다. 본 연구에서는 최근에 등장한 ASMR을 이용하여 기존 연구에서 제시된 모델들 을 비교하여 어떠한 모델이 정서표상을 잘 설명하는지 확인하고자 하였다. 본 연구에서 사용한 자료는 Kim & Kim(2022) 에서 수집한 3개의 정서유형(부정, 중립, 긍정) 및 2개의 감각양상(청각, 시청각)으로 구분된 ASMR 자극에 대한 정서평정 자료를 사용하였다. 이후, 해당 자료에 대한 다차원척도법, 표상 유사성 분석 및 이원 변량분석, 다중회귀분석 및 이원 변량 분석을 실시하였다. 다차원척도법 결과, 비부호 정서가에 비해 부호 정서가, 감각특징성에 비해 감각보편성에서 자극의 정 서유형 간 구분이 잘 이루어졌다. 다차원척도법 결과와 유사하게, 표상 유사성 분석 및 다중회귀분석 결과 또한 비부호 정서가에 비해 부호 정서가, 감각특징성에 비해 감각보편성이 유의하게 정서표상을 잘 설명하였다. 이러한 결과는 정서가 모델 중 1차원의 양극단에 긍정과 부정이 위치하는 모델이 ASMR에 대한 정서표상을 잘 설명하며, 감각양상과 상관없이 정서표상이 일관적임을 시사한다.

With about 80% of the global economy expected to shift to the global market by 2030, exports of reverse direct purchase products, in which foreign consumers purchase products from online shopping malls in Korea, are growing 55% annually. As of 2021, sales of reverse direct purchases in South Korea increased 50.6% from the previous year, surpassing 40 million. In order for domestic SMEs(Small and medium sized enterprises) to enter overseas markets, it is important to come up with export strategies based on various market analysis information, but for domestic small and medium-sized sellers, entry barriers are high, such as lack of information on overseas markets and difficulty in selecting local preferred products and determining competitive sales prices. This study develops an AI-based product recommendation and sales price estimation model to collect and analyze global shopping malls and product trends to provide marketing information that presents promising and appropriate product sales prices to small and medium-sized sellers who have difficulty collecting global market information. The product recommendation model is based on the LTR (Learning To Rank) methodology. As a result of comparing performance with nDCG, the Pair-wise-based XGBoost-LambdaMART Model was measured to be excellent. The sales price estimation model uses a regression algorithm. According to the R-Squared value, the Light Gradient Boosting Machine performs best in this model.

Due to COVID-19, changes in consumption trends are taking place in the distribution sector, such as an increase in non-face-to-face consumption and a rapid growth in the online shopping market. However, it is difficult for small and medium-sized export sellers to obtain forecast information on the export market by country, compared to large distributors who can easily build a global sales network. This study is about the prediction of export amount and export volume by country and item for market information analysis of small and medium export sellers. A prediction model was developed using Lasso, XGBoost, and MLP models based on supervised learning and deep learning, and export trends for clothing, cosmetics, and household electronic devices were predicted for Korea's major export countries, the United States, China, and Vietnam. As a result of the prediction, the performance of MAE and RMSE for the Lasso model was excellent, and based on the development results, a market analysis system for small and medium sellers was developed.

This study is to identify the maintenance service quality of eco-friendly cars, which are rapidly increasing recently. Research is conducted by synthesizing research from the perspectives of internal employees and external customers by using the service profit chain model. Specifically, it is to study the overall structural relationship between internal customer satisfaction, physical quality, interaction quality, outcome quality, external customer satisfaction and long-term orientation. For the study, 202 questionnaires were collected from internal employees and 204 questionnaires from external customers. The results of testing the research hypotheses targeting the internal employee group are as follows. As a result of testing hypothesis 1, internal customer satisfaction has a significant positive (+) effect on physical quality and interaction quality. As a result of testing hypothesis 2, the service quality of eco-friendly car maintenance has a significant positive (+) effect on each other. As a result of testing hypothesis 3, physical quality and outcome quality have a significant positive (+) effect on external customer satisfaction. The results of testing the research hypotheses targeting an external customer group are as follows. As a result of testing hypothesis 2, in the relationship between eco-friendly car maintenance service quality, physical quality has a significant positive (+) effect on interaction quality, and interaction quality has a significant positive (+) effect on outcome quality. As a result of testing hypothesis 3, interaction quality and outcome quality have a significant positive (+) effect on external customer satisfaction. As a result of testing Hypothesis 4, external customer satisfaction has a significant positive (+) effect only on intention to reuse. Finally, as a result of examining the difference in perception between the internal employee group and the external customer group in eco-friendly car maintenance service quality and external customer satisfaction, it was verified that there was a significant difference only in outcome quality and external customer satisfaction.

PURPOSES : During the summer of 2018, a heat wave (temperatures > 33°C) lasted for more than 30 days, causing blow-ups at eight different locations in South Korea. The blow-up phenomenon occurred when the internal temperature of the concrete slab increased. Simultaneously, as the concrete slab expands excessively, the length of the end of the slab increases, thus resulting in a lateral compressive force; when the slab cannot withstand this force, it rises or breaks. Blow-up is caused by a variety of factors, including increased temperature and humidity, accumulation of incompressible substances inside discontinuous surfaces, alkali–silica reactions, and aging of the concrete pavement. Several researchers have presented models to forecast blow-ups, such as the A. D. Kerr and G. Yang models, which have been applied to explain the blow-up phenomenon. However, this model has some limitations. This paper discusses a method to overcome these limitations. METHODS : Buckling, the most important theory describing the blow-up phenomenon, was reviewed, and the buckling principle was confirmed. Subsequently, the input variables of the Kerr and Yang models and the mechanism for predicting the occurrence of blow-ups were identified. The PGBA program was used to confirm the lifetime of the expansion joint and the blow-up occurrence time based on the expansion joint spacing to review the limitations of the two studied models. RESULTS : The Kerr and Yang models did not consider variables such as the expansion joint spacing or length of the integrated adjacent slab. In other words, it is necessary to reconsider the appropriateness of blow-up time predictions in relation to changes in expansion joint spacing and slab length. The expansion joint lifetime and blow-up occurrence time were predicted using the PGBA program. It was confirmed that as the expansion joint spacing increases, the expansion joint lifetime decreases. However, the blow-up occurrence time was shown to be the same (equal to 59 years), which is a limitation of the Kerr and Yang models used in the PGBA program. This resulted in a limitation in which variables for the expansion joint spacing cannot be used. CONCLUSIONS : Through blow-up simulation experiments and actual field data, an appropriate slab length should be determined, and a blow-up model should be developed based on the slab length. If a blow-up prediction based on concrete slab length and a blow-up model based on are developed, the blow-up prevention technology will be applied to the appropriate blow-up time and location to avoid traffic accidents and reduce human and property damage.

In this study, a comparative test operation was conducted through the alternate haul method to examine the selectivity of the four mesh sizes (60 mm, 90 mm, 110 mm, and 130 mm) of the trawl codend. The selectivity was analyzed using the SELECT model considering the fishing efficiency (split parameter) of each fishing gear in the comparative test fishing operation in the trawl and the maximum likelihood method for parameter estimation. A selectivity master curve was estimated for several mesh sizes using the extended-SELECT model. As a result of analyzing the selectivity for silver croaker based on the results of three times hauls for each experimental gear, it was found that the size of the fish caught increased as the size of the mesh size increased. When the selectivity for each mesh size analyzed by the SELECT model considering the split ratio was evaluated based on the size of the AIC value, the estimated split model was superior to the equal split model. Based on the master curve, the 50% selection length value was 2.893, which was estimated to be 136 mm based on the mesh size of 60 mm. In some selectivity models, there was a large deviance between observed and theoretical values due to the non-uniformity of the distribution of fished length classes. As a result, it is considered that appropriate sea trials and selectivity evaluation methods with high reliability should be applied to present trawl fishery resource management methods.

이 연구는 정부의 사회문제 해결형 연구개발사업 진화과정을 통해 사회문제 해결형 R&D 모델이 한국 사회에 자리 잡는 과정을 분석한다. 기업, 과학기술계, 시민사회에도 없었던 사회문제 해결형 R&D 모델이 정부연구개발사업을 통해 형성되고 이 모델에 따라 혁신 활동을 수행하는 조직공동체가 전개되는 과정을 살펴볼 것이다. 이를 위해 새로운 혁신모델인 사회문제 해결형 R&D 모델, 그것을 지원·수행하는 조직공동체, 새 모델을 지원하는 제도가 공진화하는 과정을 분석하는 개념적 틀을 제시한다. 그리고 이 틀을 기반으로 사회문제 해결형 연구개발사업이 진행되면서 새로운 혁신모델이 형성·발전되는 과정을 살펴보고 그 의미를 논의할 것이다. 종합에서는 사회문제 해결형 R&D 모델의 활성화를 위한 과제와 정책 방안을 다룬다.