The objective of this study is to calculate flow characteristics and structural safety for triple offset eccentric butterfly valve. The triple offset butterfly valve used in this study was 600mm in size, and the opening angles were 30 degree, 60degree and 90 degree. Structural and flow analysis of triple offset eccentric butterfly valve are carried out by using commercial code ANSYS and CFX version 14. The flow coefficient, Kv, increases as the valve opening increases. The results from fluid structure coupled analysis, maximum equivalent stress was calculated 462.06MPa at opening angle 60 degree