본 논문에서는 한국전통게임에 사용되는 접이식 종이구조물(이하 딱지)의 접이과정을 모델링하고 게임의 승리조건을 만족시키는 충돌조건을 유전알고리즘을 이용하여 산정하는 과정을 서술하였다. 딱지는 A4용지 2장으로 구성되는 것을 가정하였다. 접이과정은 강제경계조건을 부여하여 날개부분을 꼬임의 위치로 변형시키고 강체판의 강제경계조건을 이용하여 딱지를 압착하였다. 이후 복원 력에 의한 완화해석을 수행하여 게임에 사용된 딱지의 형상과 응력상태를 구성하였다. 얻어진 동일한 2개의 딱지 중 타격딱지를 주어 진 충돌위치로 강제변위에 의해서 이동시키고 주어진 충돌속력에 대한 충돌해석으로 게임의 진행과정을 해석하였다. 이 때 승리조건 인 피격딱지의 반전을 일으키는 충돌조건을 산정하기 위하여 유전알고리즘을 이용한 최적화해석을 수행하였다. 이 과정에서 효율적 인 해석을 위하여 충돌해석을 2단계로 나누고 1단계의 해석결과 피격딱지에 반전이 발생할 가능성이 있는 경우에만 2단계해석을 진 행하였다. 1단계 해석에서 유전알고리즘의 적합함수는 피격딱지의 방향코사인이었고 2단계해석에서는 속도의 역수로 하여 전체적 으로는 가장 낮은 충돌속력을 가지는 충돌조건을 찾아내고자 하였다. 해석수행결과 다양한 압착두께에 따른 최적의 충돌조건을 찾아 낼 수 있었다.

본 연구는 기초연금 지급 기준이 전체 노인에서 소득 하위 70% 노인에게 선별적으로 설계됨에 따라 필연적으로 발생하는 소득역전 현상에 주목하고, 기초연금제도의 소득역전 현상을 완화하기 위한 방안을 찾고자 시도되었다. 이를 위해 기초연금의 전신인 기초 노령연금의 소득역전 완화 효과를 분석하고, 완화구간 증가에 따른 추가소요예산을 추계 하였으며, 기존 8단계 감액 외에도 4단계, 16단계 감액 방식을 상호 비교하였다. 그 결과 소득역전 완화측면과 예산측면 모두 ‘38%～70% 감액모델’이 유리하다는 것을 확인했다. 본 연구는 소득역전 완화에 관한 몇 안되는 연구인 만큼 후속 연구에서 보다 심도 깊고 다각적인 연구가 필요하고 판단된다.

This Study is carried out to stabilize the system according to the change of superheat and subcooling in binary refrigeration system by applying cascade system. When the system on 1 st stage was started and the system on the other side was operated, a temperature reversal phenomenon occurred in which the temperature of the 1 st cascade outlet was temporarily lowered. This means that the condensate heat exchange on the 2 nd is not good, which can cause the compressor to overheated. In order to maintain stable system operation, the opening degree of the expansion valve is controlled to increase the refrigerant circulation amount, thereby facilitating the condensation heat exchange on the 2 nd stage system. We have found that the most suitable refrigerant circulation amount is found by stabilizing the operation of the system while lowerning the super low temperature from -65℃ to -70℃ and increasing again to -60℃.

Preference Reversal and Discounting Everyone has experienced “procrastination”, for example, in the context of diet, quitting smoking, doing homework, etc. Despite a desirable goal in the long term perspective, people often divert their course for a minor gain of immediate future. “Marriage blue” is a typical example of such preference reversal along a temporal dimension. Wedding seems so desirable when it is planned. But as the wedding date approaches, one starts to focus minor issues in reality and becomes hesitant to get married. Such preference reversal along a time dimension has been considered as irrational behavior, and is often referred to as present bias or time inconsistency. Fields of Behavioral Economics and Behavioral Decision Theory try to explain the phenomenon using “discounting” along a time axis. Previous research has shown three well-known properties of “discounting over time”. (1) Invalidity of exponential discounting A discount rate is not constant, but decreases rapidly at first and later more gradually. (2) Amount effect A discount rate is larger for a small amount of money than for a large amount. (3) Sign effect A discount rate is larger for gain than for loss. The first property is used to explain “procrastination”. Exponential discounting, which assumes a constant discount rate over time, cannot explain the phenomenon because two utility curves, one for a large gain in further future and the other for a small gain in near future, never cross each other over time. On the other hand, hyperbolic discounting, with a declining discount rate over time, permits the crossing, thereby explaining “procrastination”. How about “marriage blue”? Unfortunately, neither exponential nor hyperbolic discounting can explain this phenomenon. By interpreting the initial desirability as gain and the minor issues as loss, the sign effect cannot explain the reversal, either. Perhaps more complicated discounting models are necessary. However, there exist many criticisms and complications for introducing complex discounting models. Construal level theory (CLT) with a minor twist can explain “marriage blue” in a simple manner, as will be shown. What is Construal Level Theory (CLT) ? CLT, which has been receiving increasing attention in Social Psychology and Consumer Behavior Studies, posits that people’s evaluation toward items and incidents differs by the psychological distance between oneself and the object. When the distance is close, people mentally construe the object in terms of low-level, detailed, and contextualized features. In contrast, when the distance is far, they construe the same object in terms of high-level, abstract, and stable characteristics. Such difference in mental construal leads to different evaluation and behavior, and thus preference reversal. Fiedler (2007) discusses different types of psychological distances, including temporal, spatial, social, certainty-related, informational, experiential, affective, and perspective distances. Using these general notions of “distance”, CLT becomes a powerful tool to explain various preference changes. Along social distance, choice of souvenir can differ whether it is for a work supervisor or for a family member. Along spatial distance, excitement toward bungee jump in the birth country of New Zealand when leaving airport in Tokyo can change to uneasiness when arriving at Oakland airport. Along experiential distance, an advanced medical treatment, which seems attractive from an outsider’s viewpoint, can change to anxiety for risk and side effect when you are the one to receive. Because “discounting” is used to explain preference reversal with varying time distance, it is rather natural to introduce this idea into CLT with appropriate adaptation. First, discounting applies not only to time distance but also to psychological distance in general. Then, the second property, “the difference in discount rates between low versus high amount of money” shall be translated to “the difference in discount rates between low versus high construal levels”. This conceptualization, which I refer to as GCLT, can explain “marriage blue” in a straightforward manner, when the high and low construal levels of wedding are interpreted, respectively, as the initial motive and the detail issues. Generalized Construal Level Theory (GCLT) Let us summarize the three propositions of the generalized construal level (GCLT). (1) [Generalization of distance] “Discounting” applies to psychological distances including time. (2) [Amount effect] Discount rate varies depending on the construal level: the higher the construal level, the smaller the discount rate. (3) [Sign effect] Discount rate is smaller for loss than for gain. The relationship between GCLT and CLT are as follows. 1) GCLT models the consequences of CLT using the idea of discounting. It does not mean GCLT can explain what CLT cannot. 2) GCLT introduces the notion of gain and loss into CLT. 3) While CLT usually discretizes the construal level (high vs. low), GCLT regards the construal level as continuous by nature. By modeling the input and output of CLT, GCLT bypasses the complicated and arguably controversial inner mechanism/process of human perception. GCLT can predict preference and behavior shift more easily as distance varies. There is no need to specify the functional form of discounting, such as exponential or hyperbolic. When the distance is limited to time and the construal level is limited to monetary amount, GCLT becomes consistent with the ordinary “discounting” of BDT, as it should. Empirical Studies The survey asks participants to choose one of two lotteries with the same expected return: one with a higher prize amount and the other with a higher winning probability. The reason for selecting a lottery is that attributes resulting in high and low construal levels are clearly defined and same for everyone. Previous research found that, in lottery choices, prize amount and winning probability lead to high and low construal levels, respectively. In other context, it is often ambiguous what attributes result in high and low construals. Moreover, such attributes can differ by people. We investigate how lottery choice changes when the psychological distance with the subject varies. We manipulate time distance through a lottery whose outcome is announced either tomorrow (short) or one month later (longer). We manipulate social distance through a lottery which is purchased either for yourself (short) or for a prize in a party at work (long). Proposition 1 The survey asks a respondent to choose either Lottery A or B, both of which have the same expected winning outcome of 1,000 yen. A half of the sample are asked to consider two cases of time distance (tomorrow and one month later), and the other half are asked to consider two cases of social distance (for yourself and for a prize in a party at work). The design is a within-sample study. The paired McNemar test is conducted to statistically check whether the proportion of respondents valuing prize amount (high construal) over winning probability (low construal) varies by distance. The result confirms the prediction by CLT, in which, for both time and social distances, respondents’ construal levels are higher when the distance is far and vice versa. Proposition 2 A respondent is asked to choose either Lottery A or B when Lottery R, an originally intended for purchase, is unavailable. Both Lotteries A and B have the same gain or loss in expected outcome of 1,000 yen. The difference is whether the gain or loss is due to the change in the prize amount or the winning probability. A half of the sample are asked to respond to two cases of time distance (tomorrow and one month later), and the other half are asked to respond to two cases of social distance (for yourself and for a prize in a party at work). Again, the design is a within-sample study. The paired McNemar test is conducted to statistically check whether the proportion of respondents valuing prize amount (high construal) over winning probability (low construal) varies by distance. The result shows that, for social distance, the respondents’ construal levels are higher when the distance is far and vice versa, under both gain and loss. It implies higher discount rate for a low construal level. For time distance manipulation, however, changing distance did not result in the construal level change under either gain or loss. Proposition 3 A respondent is asked to choose either Lottery A or B with the same expected winning outcome when the distance is far. The survey then asks whether she would switch from her initial choice when the distance becomes close. Switch from Lottery A to B trades off the loss in prize amount over the gain in winning probability. Likewise, switch from B to A trades off the gain in prize amount over the loss in winning probability. According to GCLT, switch is likely to occur from A to B but not in the other direction. This is because discounting of a high construal level (prize amount) in loss is small whereas discounting of a low construal level (winning probability) in gain is large, the net of the loss and the gain is likely to result in sign reversal as the distance becomes close. The chi-square test is conducted to statistically check whether the proportions of respondents switching from A and from B are the same. The result shows that, for both time and social distances, there are more switches from A to B than from B to A as the distance becomes close, thereby supporting Proposition 3. Conclusions Using two samples, students and web users, the survey study largely supports the three propositions of GCLT. The only exception is the amount effect in time distance. Our study could not confirm it using neither students nor web users.

A 3-month-old American Cocker spaniel was presented at the Veterinary Teaching Hospital, Chungbuk National University, for examination of urinary tract after dissection of vaginal mass at local clinic before 10 days. Clinical examination of the affected bitch revealed a normal sized vulva in a normal anatomical position with a grossly enlarged clitoris, which contained an os clitoris. On examinations of the genital gland, there were testis, epididymis, ductus deferens and uterus. The histology of both gonads was primarily testis. Seminiferous tubules were divided into many parts by fibrous connective tissue. A small number of spermatogonia was present, but large numbers of Leydig's cells were existed. A normal female karyotype (78, XX) was detected in metaphase spreads obtained from cultured peripheral lymphocytes. Y chromosome specific sequences were not detected in genomic DNA by PCR. After 27 months, the os clitoris was larger than 3-month-old dog and os bone was more calcified than young age. Combining the results of cytogenetic, molecular genetic and histological examinations, the dog was diagnosed as a female hermaphrodite with Sry-negative XX sex reversal.

Previous studies have shown that methanol extract and its butanol fraction of Carthamus tinctorius L. Semen have the hepatoprotective effect on the CCl₄-induced hepatotoxicity. The hepatoprotective effect of subfractions has been evaluated by analyzing blood and hepatocyte biochemical analyses and biotransformation enzyme analyses. Treatment of BS-5 subfraction has significantly decreased the activities of alanine aminotransferase and aspartate aminotransferase. In addition, the levels of cholesterol and triglyceride in liver have been decreased as compared with that of CCl₄ treated rats. The hepatoprotective effect of BS-5 subfraction on the CCl₄-induced hepatotocicity would be mediated of the attenuation of the level of cytochrome P450 and the enhancement of the activity of glutathion S-transferase.

Hartmann’s procedure is most often used if immediate anastomosis is not feasible and considered very high risk of anastomotic leakage. The reversal of Hartmann operation has a significant benefit in patient's quality of life, but there are disadvantages because it is procedure of a high degree of complexity. For reversal of Hartmann operation to be truly beneficial, morbidity rate should be reasonable. The aim of this study is therefore to review clinical outcomes of the conversion of Hartmann procedure and define the complication rate of reversal of Hartmann operation in a contemporary practice. Patients undergoing an elective reversal of Hartmann’s procedure at Chosun University Hospital between January 2011 and December 2016 were included in our analysis, and the medical records were retrospectively reviewed. Total 70 patients underwent Hartmann reversal during this period. There were 33 men (47.1%) and the mean age was 67.7±14.5. The most frequent indications for Hartmann’s procedure were complicated diverticulitis in 37 patients (52.9%). Major morbidity rate was 14.3 % (10 patients), anastomotic leakage rate of 4.3% and mortality rate was 2.9% (2 patients). The most common complication was wound infection (25.7%). Univariate analysis demonstrated that there were no statistically significant variables. This study demonstrates that patients who underwent reversal of their Hartmann’s operation did not have increased postoperative morbidity based on advanced age, higher ASA score, presence of multiple comorbidities, type of operation, and longer operation time.

We previously reported that DNA hypermethylation of SRY promoter is associated with emergence of male-to-female sex reversal. The normality of offspring is achieved by relatively complete and correct nuclear reprogramming during somatic cell nuclear transfer and cloning process. The purpose of this study is to determine whether DNA demethylation of SRY promoter induced by 5-aza-2'-deoxycytidine (AzC) DNA methylation inhibitor may get back phenotypic XY sex reversal female to normal male in SCNT cloning. Canine femoral skin fibroblast cells were established from SCNT-cloned XY sex reversed female (GSF335). Using bisulfite genomic sequencing analysis, DNA methylation levels of SRY promoter in non-treated (normal) and 1uM AzC-treated cells were 88.4% and 55.3% in treatment for 4 days respectively. Seven SCNT-cloned puppies were cloned using the AzC-treated cells as donor cell. Six of those clones showed phenotypically normal male, through one puppy (GSF451) was only observed into male-to-female sex reversal with female genitalia. In umbilical cord tissue, DNA methylation levels on SRY promoter of GSF451 clone and the other clones were 79.2% and 5.7% to 62.2% respectively, which was approximately similar to those of non-treated (normal) and AzC-treated cells. Also, cloned puppies originated from AzC-treated cells implied significantly multiple body weight and height compared to age-matched SCNT-cloned control, which may be underlying in size-effect of AzC-treatment. Our findings suggest that DNA demethylated status of SRY promoter induced by AzC is likely to facilitate normal development including sex differentiation through epigenetic alteration of donor cells.

This study attempts to propose the possibility of the sex reversal in Sinonovacula constricta and Gomphina veneriformis by confirming the changes in the sex ratio with the shell length in the same population level. For analysis of sex ratio, 100 individuals of S. constricta (SL 26.5-95.0 mm) and 2385 individuals of G. veneriformis (SL 15.1-60.1 mm) were used. Sex was analyzed histologically. Both species displayed the tendency of increase in the female proportion with increase in shell length. In this study, changes in the sex ratio in accordance with the growth of S. constricta and G. veneriformis are determined to be indirect evidence that signifies their sex reversal.

To understand the sex reversal characteristics in the longtooth grouper (Epinephelus bruneus), this study examined the sex reversal and artificial masculinization of wild caught E. bruneus reared in indoor rearing tank after a 17α-methyltestosterone injection. To domesticate a broodstock, 64 wild caught E. bruneus, between 47.0 to 110.0 cm in total length and from 1.5 to 21.4 kg in body weight, were reared in indoor rearing tank (4.0 to 5.0 m wide, and 2.5 to 3.0 m depth) for four years. Seven specimens showed sex reversal from female to male during indoor rearing condition, whose total length and body weights were from 63.0 to 99.0 cm and from 4.4 to 13.2 kg, respectively. After inducing artificial masculinization in 14 female E. bruneus with a 17α-methyltestosterone (2.0 mg/kg BW) implants for 3 years, spermiation occurred in 9 specimens (total length: 54.0 to 68.0 cm, body weight: 2.3 to 4.3 kg). Among the female to male sex reversals, two specimens returned back to being female, whose body weights were 2.8 kg (initially 2.6 kg) and 2.7 kg (initially 2.3 kg). Therefore, this study suggested that E. bruneus (> 3.0 kg) was more effective in masculinizing by 17α-methyltestosterone implants.

The spatial focusing of time reversal Lamb waves on a plate has attracted considerable attention for identifying the location of an input source. This study investigates the spatial focusing performance on a plate with respect to the number of piezoelectric (PZT) sensors for varying locations of input sources. In particular, a small number of PZT sensors produce spatial focusing through the virtual sensor effect due to reflection of Lamb waves at plate edges. The spatial focusing performance with respect to the number of PZT sensors is quantified in terms of signal to noise ratio through numerical simulation and its implication is discussed

The sex ratio (F:M) in the same population of oyster, Crassostrea gigas at the commencement of the study (2007) was 1:1.0, but changed to 1:2.8 by the end of the study (2008). The sex reversal rate in two-year-old oysters was 40.2%. Specifically, female to male sex reversal rate was 66.1%, which is higher than the male to female sex reversal rate of 21.1%. The sex reversal pattern of C. gigas appears to go from male female male, and as such is determined to be rhythmical hermaphroditism.

This study attempts to propose the possibility of the sex reversal in Tegillarca granosa and Ruditapes philippinarum by confirming the changes in the sex ratio with the shell length (SL) in the same population level. For analysis of sex ratio with SL, 1500 individuals of T. granosa (SL 10.1-45.0 mm) and 712 individuals of R. philippinarum (SL 15.1-70.0 mm) were used. Sex was analyzed histologically. The average sex ratios (F:M) of T. granosa and R. philippinarum were 1:1.22 and 1:0.96, respectively. However, sex ratio was found to differ when the clams were divided into groups according to SL in 5.0 mm intervals. Both species displayed the tendency of increase in the proportion of female with increase in SL. In this study, changes in the sex ratio in accordance with the growth of T. granosa and R. philippinarum are determined to be indirect evidence that signifies their sex reversal.

We investigated the androgenic effects of 11-ketotestosterone (11-KT) on gonadal sex reversal and spermatogenesis in honeycomb grouper Epinephelus merra by method of gonadal biopsy. 11-KT was injected intramuscularly at a concentration of 1 and body weight. The proportion of cross sectional area of the gonad occupied by each germ cell type was measured and compared pre- and post-injection group. During the sex change phase, the distribution ratio of oocytes was decreased in all fish of 11-KT treatment group while the distribution ratio of spermatocytes was increased than pre-injection group. In male phase, all fish of 11-KT treatment group shown the increased distribution ratio of spermatocytes, but the distribution ratio of spermatozoa was decreased than pre-injection group. The present results suggest that 11-KT can stimulate degeneration of oocytes, proliferation of spermatocytes and spermiation in honeycomb grouper.