본 논문에서는 치조골의 흡수 유형에 따른 치근단 절제술의 수술적 평가를 수행하였다. 유한요소해석이 사용되었으며 CT 이미지를 통하여 동양 성인 여성의 상악 중절치의 3D 모델을 사용하였다. 연구에는 상악중절치의 정상저작하중조건이 적용되었다. 치조골 흡수 유형에 따른 치근 절제술의 평가를 위해 정상모델과 함께 치조골의 전체적 흡수 모델, 순측 흡수 모델 및 설측 흡수 모델을 비교하였다. 이에 따라 설측 치조골 흡수의 영향은 순측 치조골의 흡수에 비해 치아의 유지 안정성에 미치는 영향이 작음을 확인하고, 설측 치조골 흡수로 인해 치근이 노출된 환자를 대상으로 한 치근 절제술의 위험 가능성을 제시하였다.

In this study, we tried to offer the possibility of White Hibiscus syriacus L. (WHS) flower extracts as a preven-tive and improving agent of osteoporosis that bone mass reduction is induced by an decrease of osteoblast involved in boneformation and increase of bone resorption by osteoclast activity. As a results, it was found to have antioxidant activity andcontain a flavonoid contents (47.74㎎/g) of the WHS flower. There was cytotoxicity at more than 250㎍/㎖ concentration ofWHS flower extract of RANKL-induced osteoclast in RAW264.7. There were no significant inhibited TRAP activity in theWHS leaf and stem. However, it was confirmed that it is significantly inhibited the differentiation activity of osteoclasts in 50and 100㎍/㎖ concentration of cells of stability levels of only WHS flower extracts (p<0.01). The WHS flower prominentlyinhibited RANKL-induced osteoclast differentiation activity by decreased calcitonin receptor and TRAP mRNA (p<0.01).These results indicate that of osteoclasts differentiation activity is inhibited by protection of oxidative stress due to the anti-oxidant activity of the WHS flower. Therefore, suggesting the WHS flower may be a presents the possibility as a preventiveand therapeutic agents for osteoporosis.