새로운 기능성 식품소재로 그 용도가 확대되고 있는 당유도체 감미료 Fructo-oligo 당, Maltitol, Sorbitol 및 High maltose syrup의 수분 활성도 저하능력, 유산균 발효능력, 난우충성 및 상대감미도에 대하여 조사하였다. 수분활성도 저하능력은 Sorbitol이 다른 당보다 우수하였으며 Fructo-oligo 당, Maltitol은 설탕과 유사하였다. 여러 가지 유산균에 대한 발효능력은 glucose(Hydrol), Fructo-oligo 당, HMS 모두 우수하였으나 Maltitol은 Lactobacillus plantarum을 제외한 다른 유산균들의 생육을 억제하였다. Streptococcus mutans를 이용한 우충성 시험에서 Maltitol은 다른당에 비하여 뚜렷한 난우충성을 나타내었다. 당유도체들의 상대감미도는 당도수준이 높을수록 증가하는 경향을 나타내었으며 1% 설탕용액의 당도수준에서 mole 농도기준 상대감미도는 Neosugar 0.60, Sorbitol 0.21, Maltitol 0.50, HMS 0.27로 평가되었다.

This paper explores the barriers to derivative accounting disclosures in Vietnamese companies and ranks their relative importance for effective and efficient remedies. The Delphi technique was applied to get agreement of panel of experts on the measurement of factors hindering disclosure. Unstructured questionnaires were first sent to twelve experts who had both practical experience and academic knowledge in the field to get ideas on the obstructions to derivatives disclosure. The structured questionnaire was designed to get their agreement on barriers to derivative accounting disclosures. The data analysis with mean, median, mode, standard deviation, and quartile has been implemented to ensure the unanimity. Market-related factors, legislation, accountants’ attributes, managers’ attributes, information technology and communication, and on-site training were the six major obstacles agreed upon by the experts during their in-depth interviews. Then, these factors were ranked by applying the analytical hierarchy process (AHP). The findings confirmed the priority of information technology and communication, which held the greatest weight. Legislation ranked second, followed by market-related factors and on-site training, which explained the impediments to derivatives disclosure. Managers’ and accountants’ attributes had the least contribution to the barriers to derivative disclosures. The results have important implications for actions to enhance corporate derivative disclosures in Vietnam.

본 연구에서는 수용액상에서 자기조립 나노입자를 형성할 수 있는 레티노익산이 접목된 양친성 폴리아미 노산 유도체를 합성하였다. 합성한 양친성 폴리아미노산은 레티노익산의 접목도가 각각 5, 10, 30 mol%가 되도 록 조절하였다. 수용액 상에서 양친성 폴리아미노산은 소수성 레티노익산의 분자 결합에 의해 안정한 자기조립 나노입자를 형성하였다. 자기조립 나노입자는 레티노익산의 접목도가 증가할수록 크기는 작아지고 형태는 구형 에서 이중층 구조로 전이되었다. 또한 접목도가 10%일 때, 자기조립 입자의 구조 붕괴 없이 레티놀의 포집 및 전달이 가장 효과적인 것을 확인하였다. 접목도가 제어된 자기조립입자는 레티놀을 안정적으로 포집할 수 있기 때문에 주름개선제 및 다양한 기능성 화장품 전달체로 활용될 수 있다

In order to develop a sprayable ethylene antagonist, unlike 1-methylcyclopropene (MCP), we synthesized 2-decylcyclopropene-1-carboxylic acid ethyl ester (DCPE) as a derivative of cyclopropene and tested its effect on the flesh softening of ‘Fuyu’ persimmon fruits. The fruits on trees were sprayed with 4·10-4 M DCPE solution before harvest. After harvest, the persimmon fruits were stored at a low temperature for 1.5 months. The ripening progress of the fruits was then evaluated during storage at ambient temperature (20℃). Flesh softening, a measure of ethylene response, was considerably delayed up to 7 days after DCPE treatment. However control fruits was rapidly softened after 3-day storage. The treatment effect of DCPE at 4·10-4 M was also compared to that of 1-MCP at 1 ppm. DCPE was storable at refrigerated conditions for at least one month without any loss. The results show that DCPE could be a potential sprayable agent for the prevention of flesh softening of persimmon fruit.

We manufactured PVA-derived hydrogels using a foam generation technique that has been widely used to prepare colloidal gas aphrons(CGA). These gels were differentiated to the conventional gels such as for medical or pharmaceutical applications, which have tiny pores and some crystalline structure. Rather these should be used in de-pollution devices or adhesion of cells or biomolecules. The crosslinkers used in this work were amino acid, organic acid, sugars and lipids(vitamins). The structures of the gels were observed in a scanned electron microscope. Amino acids gels showed remarkably higher swelling ratios probably because their typical functional groups help constructing a highly crosslinked network along with hydrogen bonds. Boric acid and starch would catalyze dehydration while structuring to result in much lower water content and accordingly high gel content, leading to less elastic, hard gels. Bulky materials such as ascorbic acid or starch produced, in general, large pores in the matrices and also nicotinamide, having large hydrophobic patches was likely to enlarge pore size of its gels as well since the hydrophobicity would expel water molecules, thus leading to reduced swelling. Hydrophilicity(or hydrophobicity), functional groups which are involved in the reaction or physical linkage, and bulkiness of crosslinkers were found to be more critical to gel's crosslinking structure and its density than molecular weights that seemed to be closely related to pore sizes. Microscopic observation revealed that pores were more or less homogeneous and their average sizes were 20 μm for methionine, 10-15 μm for citric acid, 50-70 μm for L-ascorbic acid, 30-40 μm for nicotinamide, and 70-80 μm for starch. Also a sensory test showed that amino acid and glucose gels were more elastic meanwhile acid and nicotinamide gels turned out to be brittle or non-elastic at their high concentrations. The elasticity of a gel was reasonably correlated with its water content or swelling ratio. In addition, the PVA gel including 20% ascorbic acid showed fair ability of cell adherence as 0.257mg/g-hydrogel and completely degraded phenanthrene(10 mM) in 240 h.

비타민 C는 강력한 환원제로서 멜라닌 색소의 합성을 저해하는 것으로 알려져 있다. 그러나 일반적인 화장품 제형에서는 낮은 안정성과 경피 흡수의 문제점으로 만족할 만한 효과를 나타내지 못한다. 본 연구에서는 안정성이 개선된 비타민 C의 유도체인 ascorbyl glucoside (AsAG)을 유효성분으로 하여 경피흡수를 증가시키고자 하였다. 본 실험에서는 유연하면서도 박막 형태의 배터리를 장착한 패치 화장품을 제조하고 안정성과 경피흡수성을 평가하였다. 피부에 낮은 전류를 증가하는 이온토포레시스를 활용하여 피부에 적용하는 전류의 세기를 증가시키면 물질의 경피흡수는 증가한다. 그러나 전류의 세기를 증가시키면 피부 부작용이 증가하기 때문에 본 연구에서는 한국인의 피부에 맞는 적절한 전류를 선택하여 피부 부작용을 최소화 하였다. 이런 결과들을 바탕으로 유연하면서도 가벼운 박막 배터리를 개발하였으며, 2%의 AsAG을 함유한 이온토포레시스 패치의 안전성, 경피흡수정도, 미백효과 등을 검토한 결과 피부에 가하는 최적의 전류는 1.5 V의 배터리를 사용하여 피부 부작용과 경피흡수를 고려하여 평균 0.1 mA이었다. 또한 패치의 임상실험 결과 유의한 수준의 미백효과를 보였으며 피부 자극도도 통상의 화장품 수준을 나타냈다.