Eccentric axial load tests were carried out to investigate the structural performance of the SIP (Structural Insulation Panel), which is widely used as residential type in Europe and North America. Outside the country, design standards for SIP have been prepared and related research has been carried out variously. However, in Korea, the research on the performance of the structural insulation panel is very small, and the related standard is not provided. In this study, the eccentric axial load was applied after the opening was installed to utilize the structural insulation panel as the structural wall. The size of the test specimen was 1200 × 2400㎜. The number of test specimens was 6, and the size of the openings and the reinforcement method around the openings were used as variables.