Corni Fructus (CF) is a fruit of Cornus officinalis Sieb. et Zucc. and has been used as traditional oriental medicine. It has various functional qualities such as being antioxidative, anti-inflammatory, antidiabetic, antihyperglycemic, and immunity-regulating. In the current study, CF was extracted from two conventional extract solvents (distilled water (DW) and 70% ethanol) with/without high-speed homogenization (HSH) treatments. The extract was characterized by measuring the total polyphenol contents and antioxidant activities. The HSH treatment significantly improved the total polyphenol content (from 28.4±0.9 mg/mL to 35.5±0.9 mg/mL), ABTS (from 59.8±0.4% to 78.4±2.7%), and DPPH radical scavenging activities (from 50.8±1.4% to 59.7±2.8%) of the DW extract and showed a level similar to that of 70% ethanol extract. The CF extracts were further used to prepare functional jelly with gelatin and other components such as pectin, fructooligosaccharide, and citric acid. The jelly’s hardness, springiness, gumminess, and cohesiveness were characterized using a texture profile analysis (TPA).

목적 : 본 연구는 한국표준산업분류에 따라 산재환자의 작업능력평가 세부항목 실시 데이터를 분석하여 업종별 직장복귀프로그램의 기초자료를 제시하는데 있다. 연구방법 : 후향적 코호트 조사 연구로 근로복지공단 소속병원의 전자의무기록을 활용하여 2018년 1월부터 2020년 12월까지 작업능력평가를 실시한 2,145명의 산재환자의 기초분석과 한국표준산업분류에 따라 건설업, 제조업, 전문ㆍ기술업, 시설 관리 및 서비스업, 운송업, 보건업 및 사회복지 서비스업으로 분류한 후 대상자들에게 시행된 작업능력평가 세부항목의 수행 빈도 차이를 분석하였다. 결과 : 작업능력평가에 참여한 대상자는 남성 1,798명(83.8%), 여성 347명(16.2%)이었으며, 연령대는 50-59세가 790명(36.8%)으로 가장 많았다. 산재 요양시작 이후 평균8.83 ± 5.32개월 시점에 평가가 이루어졌다. 제조업 692명(32.3%), 건설업 642명(29.9%), 전문ㆍ기술업 308명(14.4%)이 대부분이었고 손상 부위는 하지 손상이 736명(34.3%)으로 가장 많았다. 작업능력평가 시 포함된 세부 평가항목 중 어깨높이에서 밀기ㆍ당기기, 작업장 이동에서 걷기, 기어가기, 자세유지평가에서 무릎 꿇기 작업을 제외한 모든 항목에서 직업에 따라 유의한 차이가 있었다. 특히, 건설업에서 들기와 옮기기의 수행 빈도가 높았고, 가장 무거운 무게까지 평가를 했으며, 제조업에서는 자세유지평가 빈도가 높았다. 결론 : 본 연구에서 작업능력평가에 참여한 산재환자의 동향과 한국표준산업분류에 따라 실시되는 작업능력평가 세부항목 차이를 확인하여 임상에서 참고할 수 있는 기초자료를 제시하였다.

현재 도로나 보도의 포장은 콘크리트 포장, 아스콘 포장, 석재 포장, 자갈 포장, 흙 포장, 목재 포장, 우레탄 포장, 고무칩 포장, 블록 포장 등이 시공되고 있으며, 그 중 수지와 합성고무 칩 또는 우레탄 칩 등을 혼합한 다양한 재질의 탄성포장재 가 주로 사용되어지고 있다. 이러한 탄성포장재는 탄성이 좋고 사용성이 좋으나, 2000년대 들어서면서 화학제품에 대한 환경유해성 논란이 대두됨에 따라 탄성 포장재에 대한 환경문제가 제기되었다. 따라서 이 연구에서는 친환경 소재인 알톱밥과 EPDM 칩을 사용하여 친환경 포장재의 개발을 목적으로 하였다. 휨강도 시험, 인장강도 및 신장률 시험, 투수성 시험, 중금속 및 유해 화학물질 총량 시험, 폼 알데하이드 방출량 시험, 경제성 분석을 통해 탄성 포장재에 대한 한국산업규격 KS F 3888-2 및 기존 논문들과 비교 분석하여 이 연구에서 제시한 포장재의 역학적 특성과 환경 유해성 물질 기준을 제시하였다.

This study aim to evaluate dietary quality and nutritional status according to the consumption of health functional food using Nutrition Quotient for Korean elderly (NQ-E) for 288 elderly people attending senior welfare centers in Gyeonggi-do. The questionnaire consisted of items about general information, health functional food, and Nutrition Quotient for Korean elderly (NQ-E). Chi-squared test, Fisher's exact tests, and Analysis of Covariance (ANCOVA) were performed using the SAS program ver. 9.4. Among the male and female subjects, the female subjects consumed more health functional food. The results of the dietary quality and nutritional status difference according to the intake of health functional food showed significant differences only in the areas of variety and abstinence among nutrition quotient factors for men, while no significant differences were observed in any of the nutrition quotient factors for women. In conclusion, focused-nutrition education program and useful guideline is needed for promoting adequate consumption of health functional foods in elderly.

This study was conducted to explore the quality characteristics of colored rice depending on the cultivars (Jeogjinu, Josaengheugchal, Joeunheukmi, Heukjinjubyeo, Hongjinju, Heukjinmi, Geongganghongmi) for porridge. The moisture, crude protein, lipid, ash, amylose and damaged starch contents of colored rice ranged from 10.05~11.23%, 7.72~8.69%, 2.68~3.26%, 1.62~1.88%, 6.29~20.31% and 5.06~8.26%, respectively. The highest moisture (11.23%), crude protein (8.69%), lipid (3.26%) and ash (1.88%) contents of colored rice were detected in Heukjinjubyeo, Joeunheukmi, Josaengheugchal and Heukjinmi, respectively. The lowest amylose and damaged starch contents of colored rice were detected in Josaengheugchal and Joeunheukmi, respectively. In general, the water binding capacity, water solubility and swelling power of Heukjinmi were greater than those of the other cultivars. The investigation of the pasting properties (peak, trough, break down, final and setback viscosity, peak time, pasting temperature) of colored rice indicated a low value in Josaengheugchal. The lowest hardness (13,673.25 g) of colored rice was observed in Heukjinjubyeo while the highest digestibility (5.44 glucose mg/g) of colored rice was observed in Josaengheugchal. These results indicated that Josaengheugchal are suitable cultivars for porridge.

Background: Functional capacity evaluations (FCEs) are designed to systematically assess the capacity to perform work-related tasks and to determine worker’s ability to return to the previous job following work-related injuries. These evaluations may be rated either by clinician or worker. There has been a lack of consensus between the two scoring methods. Objects: This study aimed: 1) to confirm if the data are fit to the Rasch rating scale model and 2) to investigate the item-level concordance rate between the ratings of clinician and injured worker of the FCE. Methods: A cross-sectional study was conducted with a sample (n=124) of a rehabilitation program with the Occupational Rehabilitation Data Base for workers with low back pain. The functional capacity evaluation at admission and discharge was administered to clinicians and workers. The data were analyzed using both classical test theory-based Pearson’s r and intra-class coefficient followed by item-level analysis with Rasch rating scale model. Results: All items of the FCE, except sitting items rated by clinician at admission and handling items rated by both clinician and worker throughout admission and discharge, were acceptable fit statistics with minor out of ranges for a misfit criterion. This may indicate that the items of the FCE overall fit to the Rasch rating scale model. Few problematic items responding differently to clinician and worker both at admission and discharge were detected with the differential item functioning analysis despite the excellent concordance rate using the two conventional statistics-sitting and handling items at admission and handling item at discharge. Conclusion: The item-level speculations using Rasch analysis of the FCE demonstrate that the ratings of clinician and self ratings of worker were psychometrically acceptable though there was an apparent discrepancy between the raters both at admission and discharge.

This study is intended to evaluate the value of functional aspect from the viewpoint of habitat. The indicators that are used in biotope evaluations are various, but most of them use the criteria to evaluate the naturality. This evaluation method cannot appropriately reflect the functional characteristics coming from relation to the surrounding biotope. In this study, the connectivity, cohesion and diversity between individual biotope are quantitatively measured by a landscape index. It is hard to draw the functional value of individual biotopes because the landscape index related to connectivity, cohesion and diversity comes from a landscape having a number of biotopes. The concept of contribution was used to overcome this limitation. The concept of contribution is to quantify how much each individual biotope contributes to the connectivity, cohesion, and diversity in a certain range of landscape by deriving the amount of change in the landscape index according to the presence or absence of each individual biotope. In order to understand the characteristics of evaluation results in functional aspect, this research has done a comparative analysis of the previous research findings in the same target area. According to the result of the research, individual biotopes such as artificial forests, fragmented natural forests, and small planting sites were highly rated.

A tissue cultured wild ginseng (TCWG) suspension was inoculated with lactic acid bacteria and fermented to improve the functionality of TCWG. The utilization of TCWG was increased directly using the freeze-dried powder. The optimal ratio of TCWG powder and water for fermentation was 1:19 (5%), which was selected by measuring the fluidity and viable cell count according to concentration. The effects on ADH activation and immune cell activation by each ferments with 10 kinds of Lactobacillus sp. strains were examined. The ferments with the Lactobacillus casei KFRI 692 strain showed 5.4 times higher ADH activity and 1.3 times higher ALDH activity than the non-fermented TCWG powder (control). The level of NO production and cytotoxicity was also measured by Raw 264.7 cells. The ferment with the Lac. casei KFRI 692 strain showed the highest level of NO production and lower cytotoxicity than the others. Therefore, the Lac. casei KFRI 692 strain was selected as a strain for fermentation of a TCWG suspension to maximize its functionality. To identify the optimal fermentation time of the selected Lac. casei KFRI 692 strain on the 5% TCWG suspension, the viable cell count of lactic acid bacterial and the changes in pH were observed for 72 hours. 24-hrs was found to be the optimal fermentation time. In this way, fermented TCWG with lactic acid bacteria showed higher ADH activation efficacy and immune cell activation than non-fermented TCWG.

배수성 포장에 있어 기능적 평가인 투수성 실험과 더불어 소음저감 측정을 서울시에서 시공한 구간에서 실시하였다. 소음측정은 두 가지 방법을 이용하였는데 그 방법은 Pass-by 방법과 NCPX(Novel Close Proximity) 방법을 이용하였다. Passby 방법은 교통량에 따른 소음원이 전달되는 것을 측정하는 방법이고, NCPX는 타어어와 포장 표면간의 마찰음을 측정하는 방법이다. 현장투수시험을 위해서는 총 5개의 구간에서 실시하였으며 각 구간마다 주행부와 비주행부로 나뉘어 측정하였다. 3개 구간의 Pass-by 측정을 위해서는 교통소음원 발생점으로부터 인접한 곳에서 측정을 실시하였고 또한 공원내부 혹은 단지 내부에서도 소음을 측정하였다. 마지막으로 NCPX 측정은 4군데서 실시하였다. 결과적으로 배수성 포장의 기능인 투수성과 소음저감이 2, 3년 사이에서는 그 기능을 잘 유지함을 알 수 있었다.

One of the most important objectives of post-marketing monitoring of dietary supplements is the early detection of unknown and unexpected adverse events (AEs). Several causality algorithms, such as the Naranjo scale, the RUCAM scale, and the M&V scale are available for the estimation of the likelihood of causation between a product and an AE. Based on the existing algorithms, the Korea Food & Drug Administration has developed a new algorithm tool to reflect the characteristics of dietary supplements in the causality analysis. However, additional work will be required to confirm if the newly developed algorithm tool has reasonable sensitivity and not to generate an unacceptable number of false positives signals.

주된 도시들의 불투수성 포장화에 따른 현상으로 토양의 사막화를 일으키고 있으며, 나아가, 도시 온난화 현상을 발생시켜 도시지역의 평균 온도를 올리는 원인이 되고 있다. 이로 인해 우수가 투수성 토양에 흡수되거나 잔류되어야 하는 양이 줄어듦에 따라 자주 도심지내에서 범람이 되는 현상을 보여주고 있다. 결국은 우수시스템이 제대로 작동하지 않고 침식이 발생하고 있다. 투수성 포장시스템과 관련해서는 블록 포장이 여러 군데서 수년 동안 사용되어 왔다. 또한 투수성 블록 포장은 전통적으로 사용된 아스팔트 포장 및 콘크리트 포장에 비해 다양한 형태로 사용될 수 있는 장점과 더불어 타 포장보다 미적으로 낳은 면을 보여 주고 있다. 따라서 도로의 현장 조건을 모사하기 위해 본 연구에서는 실험용 슬러지 및 휠 트래킹 장비를 이용한 블록 포장의 기능적인 투수성 평가를 실시하였다.

We investigated eight active natural antimicrobials for preservation of functional beverages that are usually degraded by yeasts rather than by bacteria due to a high sugar content and a low pH. Five strains of yeasts (S. cerevisiae, Z. bailii, P. membranaefaciens, C. albicans, and P. Anomala) were tested with eight natural antimicrobial agents (ε-polylysine, yucca extract, vitamin B1 derivative, scutellaria baicalensis extract, chitooligosaccharid, allyl isothiocyanate, sucrose-fatty acid ester, and oligosaccharide). The lowest minimal inhibitory concentrations (MIC) were 10 ppm for oligosaccharide and sucrose-fatty acid ester against S. cerevisiae and Z. bailii, 10 ppm for allyl isothiocynate against P. membranaefaciens and C. albican, and 10 ppm for allyl isothiocynate and oligosaccharide against P. anomala . No growth were observed for five kinds of yeasts in functional beverages containing sodium benzonate at concentration of 0.015% or higher. The resistance of S. cerevisiae, Z. bailii, and P. Anomala against natural antimicrobial agents was lower than those of P. membranaefaciens and C. albican. Allyl isothiocyanate, oligosaccharide, and sucrose- fatty acid ester showed the highest antimicrobial activities among the eight tested antimicrobials. These results can be applied to develop new natural antimicrobial agents to improve microbial quality of functional beverages.