This study was carried out to investigate the vascular plants of Mt. Nochu (1,322m) from April, 2014 to October, 2015. The vascular plants were summarized as 515 taxa, including 89 families, 304 genera, 448 species, 4 subspecies, 57 varieties and 6 forms. Among the investigated 515 taxa, 11 Korean endemic plants and 14 rare and endangered plants were included. The floristic regional indicator plants found in this area were 11 taxa of grade IV, 30 taxa of grade III. Naturalized plants consisted of 24 taxa that made up 4.6% of the total vascular plants in this area. Medicinal plants of the Korean Pharmacopoeia and Korean Herbal Pharmacopoeia distributed in this area consisted of 67 taxa.

Background : This study was carried out to investigate the antioxidant activities and the contents of antioxidant compounds in extracts derived from 24 medicinal crops. Methods and Results : Dried plant materials were extracted by methanol. The extracts of each plant were evaporated under vacuum and stored in deep freeze at -20℃ until use. The levels of total phenolic compounds were much higher in Evening primrose, Houttuynia cordata, Chinaberry, Sumac, Gaeddongssuk, Giant knotweed and Dendropanax morbifera compared with other crops. On the other hand, the total phenolic compound levels in Safflower, Fleeceflower root, Gingko, Black nightshade, Saposhinikovia root, and Maize woody pith were relatively low. The total flavonoid contents were highest in Houttuynia cordata, followed byDendropanax morbifera, Gaeddongssuk, Aralia cordata and Evening primrose. DPPH activity was significantly higher in Gaeddongssuk, Sumac, Chinaberry, Dendropanax morbifera and Evening primrose, and ABTS activity was significantly higer in Sumac, Chinaberry, Evening primrose, Giant knotweed, Gaeddongssuk and Dendropanax morbifera than other plants. The antioxidant activities dertermined in all assays positively correlated with the total phenolic compoubds (0.619≤ r ≤0.895) and flavonoid contents (0.488≤ r ≤0.619) as well as among themselves (r=0.900). Conclusion : These results suggest that Evening primrose, Gaedongssuk, Sumac, Dendropanax morbifera, and Giant knotweed can be utilized as food additives and natural antioxidants due to their strong antioxidant activity.

본 연구는 반추위 메탄저감용 약용식물 첨가제 개발을 위해 유산균을 이용하여 발효한 두충 및 감초 추출물의 항균활성, 항산화활성 및 in vitro 반추위 발효시험을 실시하였다. 발효 약용식물 추출물 제조를 위해 접종된 종균의 성장효율을 조사하기 위해 실시한 생균수 측정 결과 L. curvatus NJ40, L. brevis NJ42 및 L. plantarum NJ45가 두충과 감초 모두에서 유의적으로 높은 균주 성장을 나타냈다(p<0.05). 항균활성측정 결과는 두충과 감초 추출물에서 공통적으로 L. curvatus NJ40 및 L. plantarum NJ45 로 발효한 추출물이 일부 병원균에 대한 항균효과를 나타내는 것으로 조사되었다. In vitro 반추위 발효시험에서 두충 및 감초 발효 추출물을 적용한 결과, 감초 추출물에서 메탄 저감효과가 나타났다. 특히 반추위내 미생물 발효 특성을 대표할 수 있는 휘발성지방산 생성효율을 향상 시키면서, 전반적 반추위 발효에 부정적 영향이 없는 것으로 나타났다.

국내 식물자원 및 약용식물들의 식물 생장촉진 효과를 조사하기 위하여 64종 65점의 추출물 시료를 조제하여 벼(Oryza sativa) 유묘 생장에 미치는 영향을 평가하였다. 그 결과, 11종 12점의 쑥(Artemisia princeps) 경엽, 엉겅퀴(Cirsium japonicum var. maackii) 전초, 진달래(Rhododendron mucronulatum) 가지와 잎, 갈대(Phragmites communis) 줄기, 율무(Coix lacrymajobi var. mayuen) 전초, 싸리(Lespedeza bicolor) 가지와 잎, 산수국(Hydrangea serrata f. acuminata) 전초, 속단(Phlomis umbrosa) 전초, 감초(Glycyrrhiza uralensis) 근경, 감초(G. uralensis) 경엽, 당귀(Angelica gigas) 뿌리 및 천궁(Cnidium officinale) 근경 추출물은 벼 유묘 생장을 촉진시키는 것으로 나타났다. 본 결과에 따라 상기 식물 종의 부위들은 식물 생장 촉진용 농가 자가제조 액비 개발을 위한 소재로써 활용가능성이 있는 것으로 판명되었다.

본 연구에서는 20종 생약 열수추출물의 AChE 활성, 산화 스트레스로 인한 지질 과산화물 생성 억제능 및 뇌신경 세포 사멸에 대한 보호효과를 비교하였다. AChE의 억제활 성은 산수유, 감초, 당귀 열수추출물에서 우수하였으며, 그 중 산수유가 가장 높은 억제율을 나타내었다. 또한 H2O2/ FeSO4로 산화 스트레스를 유발시켜 생약 열수추출물의 지 질과산화물 생성 억제 활성을 조사한 결과 소엽, 하수오, 계피 및 감초 열수추출물에서 높은 항산화 활성을 보였다. L-Glutamate에 의해 유도된 신경세포 독성에 대한 보호효 과는 감초, 계피, 길경, 박하 열수추출물의 100 μg/mL 농도 에서 관찰되었다. 본 연구를 종합적으로 살펴보았을 때, 감초 열수추출물이 치매 예방 및 개선제로써의 활용가능성 이 가장 뛰어난 것으로 판단된다. 향후 치매예방 효능을 가지는 새로운 화합물 발굴을 위한 기초자료로 활용될 것으 로 사료된다.

This text was analyzed and investigated the distribution of medicinal plants in Cheongoksan Bonghwagun Korea, in order to search the medicinal resources that are used in modern medicine. Medicinal plants of the Korean Pharmacopoeia (10th edition) distributed in Cheongoksan Bonghwagun were consisted of 93 taxa ; 82 species, 10 varieties, 1 forma of 79 genus, 50 families. In medicinal plants of the Korean Pharmacopoeia, rate of native species and exotic species was 89.2% (83 taxa) and 10.8% (10 taxa) respectively. Family classification was the most of compositae of 8 taxa, and life form classification was most of herb of hemicryptophyte species. The classification by using parts were 34 taxa of root use and the classification of efficacy utilization was 24 taxa of Cheongyeolyak (heat-clearing drug) use.

We studied the total polyphenol content, DPPH radical scavenging activity, hydroxyl radical scavenging activity and α-glucosidase inhibition of water extracts from 17 medicinal plants. Total polyphenol contents ranged from 10.0 (Coix lachryma-jobi L, CL) ~ 279.7 (Perilla sikokiana, PS)mg/g. The water extract from medicinal plants were evaluated for its free radical scavenging activities and compared with a commercial antioxidant, ascorbic acid. DPPH radical scavenging activity of Pyrus pyrifolia (PP), Chamaecyparis obtusa L. (COL), Chamaecyparis obtusa F. (COF), and PS were higher than positive control. Higher hydroxyl radical scavenging activity were shown in Acanthopanax senticosus (AS) and Cordyceps militaris (CM) than the other plants. The highest anti-α-glucosidase activity was observed in Cornus officinalis (CO) and Paeonia suffruticosa Andrews (PSA) water extracts. PSA showed not only the higher DPPH radical scavenging activity but also the anti-α-glucosidase activity. The results of our study that PP, COL, COF, PS, AS, CM, CO and PSA could be potential candidates for natural antioxidants.