The insects have been investigated as novel sources for foods and biomaterials in several recent studies. However,its effects on hair growth have not been sufficiently researched. To develop novel and natural materials for preventingalopecia and promoting hair growth, we investigated the antioxidant activity and hair growth promoting effect of Tenebriomolitor larvae extract (TME). As a result, DPPH radical scavenging activity was 81.17%, and nitrite scavenging activitywas 43.69%, which were similar to blueberry extract. And TME promoted the proliferation of human DPCs and NIH3T3cells, concentration dependently. In addition, the TME prevented not only DHT-induced DPCs cytotoxicity but also actionof TBM as a potassium channel blocker in NIH3T3 cells. These results suggest that TME can be used as a functionalmaterial for alopecia therapeutic reagent by preventing hair loss and promoting hair growth.

• Minchul Seo(Department of Agricultural Biology, National Institute of Agricultural Sciences)
• Mi-Ae Kim(Department of Agricultural Biology, National Institute of Agricultural Sciences)
• Eun-Young Yun(Department of Agricultural Biology, National Institute of Agricultural )
• Jae-Sam Hwang(Department of Agricultural Biology, National Institute of Agricultural Sciences)
• Minhee Baek(Department of Agricultural Biology, National Institute of Agricultural SciencesSciences) | Minhee ba다