The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of green tea, mulberry leaf, licorice, and propolis, which are reported to have antimicrobial activities, were selected and used in this study. The minimum inhibitory concentrations (MIC) of extracts on periodontal pathogens such as Fusobacterium nucleatum and Porphyromonas gingivalis and their synergy effects with oraCMU by the fractional inhibitory concentrations methods were measured. From the results obtained, all the extracts showed no effect on the growth of oraCMU. Green tea extract showed the best antibacterial activity with MIC of 1.8 mg/ml against both F. nucleatum and P. gingivalis. In addition, green tea extract had a synergistic effect with oraCMU against F. nucleatum. Therefore, these results suggested that green tea extract is available as an additive in oral health food made with oraCMU.

서 론
 재료 및 방법
  천연추출물이 oraCMU의 생장에 미치는 영향
  천연추출물의 치주병원균에 대한 항균 효과
  oraCMU의 치주병원균에 대한 항균 효과
  녹차 추출물과 oraCMU의 항균 시너지 효과
  통계처리
 결 과
 고 찰
 References

• Ji-Eun Yeu(Research Institute, Oradentics Inc.)
• Hyun-Jin Kim(Institute of Biomaterial Implant, Department of Oral Anatomy, School of Dentistry, Wonkwang University)
• Mi-Sun Kang(Research Institute, Oradentics Inc.) Correspondence to