KOREASCHOLAR

Screening of a new mushroom having xanthine oxidase inhibitory activity for development of new anti-gout agent

Jung-Hwa Song, Bolormaa Zanabaatar, Jeong-Hoon Jang, Hyung-Jun Noh, Young-Bok Yoo, Jong-Soo Lee
  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/276305
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한국버섯학회지
제8권 제2호 (2010.06)
p.82
한국버섯학회 (The Korean Society of Mushroom Science)
초록

This study was carried out to obtain new anti-gout agent from mushrooms. Various extracts from twelve kinds of mushrooms were prepared by water and ethanol extractions and its anti-gout xanthine oxidase inhibitory activity were investigated. Water extract of Flammulina velutipes and Agaricus bisporus fruiting bodies showed high xanthine oxidase inhibitory activity of 70.8% and 60.0%, respectively. However, its inhibitory activity of these ethanol extracts were very low excepet 60.3% of Innotus obliquus. Finally, we selected Flammulina velutipes, showing the highest xanthine oxidase inhibitory activity as a producer of new anti-gout agent.

키워드
저자
  • Jung-Hwa Song(Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea)
  • Bolormaa Zanabaatar( Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea) | Bolormaa Zanabaatar
  • Jeong-Hoon Jang( Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea) | Jeong-Hoon Jang
  • Hyung-Jun Noh( National Institute of Agricultural Science and Technology, Suwon 441-707, Korea) | Hyung-Jun Noh
  • Young-Bok Yoo( National Institute of Agricultural Science and Technology, Suwon 441-707, Korea) | Young-Bok Yoo
  • Jong-Soo Lee( Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea) | Jong-Soo Lee