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상황버섯, Phellinus linteus 계통과 Phellinus baumii 의 항 혈소판 응집 효과 Inhibitory effects of Sanghwang mushrooms, Phellinus linteus strains and Phellinus baumii, on platelet aggregation

강희완, 이만휘, 여운형
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한국버섯학회지
제15권 제3호 (2017.09)
pp.124-128
한국버섯학회 (The Korean Society of Mushroom Science)
초록

The fruiting bodies of Sanghwang mushrooms, Phellinus linteus HN1009K (PLH) and Phellinus linteus (Korea Sanghwang, PLK), and Phellinus baumii (Jangsu Sangwhang, PB), were extracted with 70% methanol. The methanolic extracts of different concentrations (5–200 μg/ml) showed inhibitory effects of 20–95% on plated aggregation induced by collagen (2.5 ug/ml), ADP (10 uM), and thrombin (0.1 U/ml). The PLH, PLK, and PB extracts (200 ug/ml) reduced ATP release from ADP-activated platelets by 50¬60%. These results suggest that the methanolic extracts from Sanghwang mushrooms inhibit platelet aggregation.

키워드
Anti-platelet AggregationATP releaseMethanolic extractsSanghwang mushrooms
저자
  • 강희완(한경대학교원예생명과학과)
  • 이만휘(경북대학교 수의과대학)
  • 여운형(케이티엔지 R&D 본부)