To search a new pig pheromonal odorant, the N1-allyl-N2-(tetrahydrofuran-2-ylmethyl)oxalamide molecule predicted by ligand based approach and molecular docking method was synthesized by nucleophilic addition-elimination reaction (AdNU-E) between N-allyloxalamic acid ethylester and tetrahydrofurylmethylamine. According to the evaluation results for efficiency of pig estrus control, the synthesized pig pheromonal N1-allyl-N2-(tetrahydrofuran-2- ylmethyl)oxalamide molecule advanced the estrus by 11.3 days (p<0.05) compared with the non-pheromone group. And from these results, it is predicted that the synthesized pig pheromonal compound will be able to increase the reproduction efficiency of pig.

ABSTRACT   서론   재료 및 방법    시약 및 기기    N-allyloxalamic Acid Ethylester (2)의 합성    N-a11y1-N'-(tetrahydrofurane-2-y1methy1)oxa1amide(3)의 합성    시료저장 용액의 제조    돼지 발정유발 실험   결과    돼지 페로몬성 분자    돼지발정 동기화   고찰    돼지 페로몬성 분자의 합성    저장 용액 및 돼지 발정 동기화   인용문헌

• 박창식(충남대학교 형질전환복제돼지연구센터) | Chang-Sik Park
• 송석오(충남 축산기술연구소) | Suck-Oh Song
• 임재삼(충남 축산기술연구소) | Jae-Sam Lim
• 성민규(충남대학교 농업생명과학대학 응용생물화학부) | Min-Gye Soung
• 성낙도(충남대학교 농업생명과학대학 응용생물화학부) | Nack-Do Sung Corresponding author