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Antidiabetic Activities Analysis by Oral Glucose Tolerance Test in Rats

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한국동물번식학회 (The Korean Society of Animal Reproduction)
초록

In this study, we conducted an oral glucose tolerance test (OGTT) so as to compare antidiabetic activities of general potatoes, purple-flesh potatoes, and potato pigments in rats at various concentration levels. After allowing the rats to abstain from food for 12 hours, 10%/20% general potato, purple-flesh potato, and potato extract was orally administered to rats at 100 and 500 mg/kg concentrations. The blood glucose level was measured after an hour. Then, immediately, 1.5 g/kg of sucrose was administered through the abdominal cavity and the blood glucose measured after 30, 60, 120, and 180 minutes. 20% purple-flesh potato group and 10% general potato group, both 100 and 500 mg/kg, showed a significant concentration-dependent decrease in blood glucose levels after 30 minutes. The 100 mg/kg potato pigment group also showed a statistically significant decrease after 30 minutes. In conclusion, administration of 10% general potato, 20% purple-flesh potato, and potato pigment can reduce blood glucose level in an OGTT using rats.

목차
ABSTRACT   INTRODUCTION   MATERIALS AND METHODS    Materials    Animals    Oral Glucose Tolerance Test    Statistical Analysis   RESULTS   DISCUSSION   REFERENCES
저자
  • Myung-Hwa Kang(Dept. of Food Science and Nutrition, Hoseo University)
  • Mi-Kyeong Choi(Dept. of Food and Nutrition, Kongju National University) Corresponding author