It is not easy to predict the shrinkage rate of a plastic injection mold in its design process. The shrinkage rate should be considered as one of the important performances to produce the reliable products. The shrinkage rate can be determined by using the CAE tools in the design produces. However, since the analysis can take minutes to hours, the high computational costs of performing the analysis limit their use in design optimization. Therefore this study was carried out to presume for mutual relation of analysis condition to get the optimum average shrinkage by regression analysis. The results shown that coefficient of determination of regression equation has a fine reliability over 87% and regression equation of average shrinkage is made by regression analysis